| Autor: |
Wu, Yi-Ying, Hung-Chang Wu, Wu, Jia-En, Kuo-Yen Huang, Shuenn-Chen Yang, Si-Xuan Chen, Chao-Jung Tsao, Keng-Fu Hsu, Yuh-Ling Chen, Tse-Ming Hong |
| Rok vydání: |
2019 |
| Předmět: |
|
| DOI: |
10.6084/m9.figshare.8426003.v1 |
| Popis: |
Figure S1. The dose determination for BEZ235 and cisplatin in the in vivo study. Figure S2. Viability of BEZ235-treated NSCLC cell lines expressing wild-type EGFR or activating mutants of EGFR. Figure S3. Regrowth of BEZ235-treated NSCLC cells after withdrawal of the drug. Figure S4. Effects of BEZ235 on apoptosis, autophagy and cell cycle. Figure S5. β-catenin is not involved in the BEZ235-induced decrease in cyclin D. Figure S6. BEZ235 synergistically enhances cisplatin-induced apoptosis in NSCLC cells. Figure S7. BEZ235 synergistically enhances BIBW2992-induced apoptosis in EGFR-TKIâ resistant NSCLC cells. (PDF 1190 kb) |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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