Development of Au nanowire injector system to deliver plasmid into mouse embryo
| Autor: | Jeong Mook M. Lim, Yun Mi M. Lee, Ji Yeon Y. Ahn, Eun Joo Lee, Mijeong Kang, Yoori Sung, Taejoon Kang, Bongsoo Kim, Kkotchorong Park, Keun Cheon Kim, Hyoban Lee |
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| Rok vydání: | 2017 |
| Předmět: |
0301 basic medicine
animal structures Nanowire 02 engineering and technology Gene delivery Biology lcsh:Computer applications to medicine. Medical informatics 03 medical and health sciences Plasmid Research article lcsh:Science (General) Multidisciplinary Mosaicism Embryo Gold nanowire Nanoinjector 021001 nanoscience & nanotechnology Molecular biology Cell biology Chemistry 030104 developmental biology Transgenic animal embryonic structures lcsh:R858-859.7 0210 nano-technology lcsh:Q1-390 |
| Zdroj: | Data in Brief Data in Brief, Vol 14, Iss C, Pp 48-55 (2017) |
| ISSN: | 2352-3409 |
| DOI: | 10.1016/j.dib.2017.07.017 |
| Popis: | In this data article, we developed a Au nanowire injector (Au NWI) for directly delivering plasmid into the 1-cell stage of the mouse embryos designed to successfully attach and detach the plasmid on the Au NWI, highly minimizing physical and chemical damage on the embryos. This data presents that a Au NWI system does not induce detrimental damages on development of embryos and efficiently express the green fluorescence protein in vitro. The data provided herein is in association with the research article related to reduce the occurrence of mosaicism by a Au NWI,” Suppressing Mosaicism by Au Nanowire Injector-driven Direct Delivery of Plasmids into Mouse Embryos” (Park et al., 2017 [1]). |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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