Early onset of pulmonary gas exchange disturbance during progressive exercise in healthy active men
| Autor: | J. Ochier, Hélène Perrault, J. Maitre, B. Aguilaniu, J. R. Lacour, P. Flore |
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| Rok vydání: | 2002 |
| Předmět: |
Adult
Male medicine.medical_specialty Disturbance (geology) Physiology Physical Exertion Physical exercise Competitive athletes Submaximal exercise Body Temperature Hypoxemia Oxygen Consumption Physiology (medical) Internal medicine Tidal Volume Humans Medicine Respiratory system Exercise Early onset Pulmonary Gas Exchange business.industry Arteries Respiratory Dead Space Respiration Disorders Respiratory Function Tests Physical Fitness Exercise Test Physical therapy Cardiology Bicycle ergometer Blood Gas Analysis medicine.symptom business |
| Zdroj: | Journal of Applied Physiology. 92:1879-1884 |
| ISSN: | 1522-1601 8750-7587 |
| DOI: | 10.1152/japplphysiol.00630.1999 |
| Popis: | 10.1152/japplphysiol.00630.1999.—Some recent studies of competitive athletes have shown exercise-induced hypoxemia to begin in submaximal exercise. We examined the role of ventilatory factors in the submaximal exercise gas exchange disturbance (GED) of healthy men involved in regular work-related exercise but not in competitive activities. From the 38 national mountain rescue workers evaluated (36 ± 1 yr), 14 were classified as GED and were compared with 14 subjects matched for age, height, weight, and maximal oxygen uptake (V˙o 2 max; 3.61 ± 0.12 l/min) and showing a normal response (N). Mean arterial Po 2 was already lower than N ( P= 0.05) at 40% V˙o 2 max and continued to fall until V˙o 2 max (GED: 80.2 ± 1.6 vs. N: 91.7 ± 1.3 Torr). A parallel upward shift in the alveolar-arterial oxygen difference vs. %V˙o 2 max relationship was observed in GED compared with N from the onset throughout the incremental protocol. At submaximal intensities, ideal alveolar Po 2, tidal volume, respiratory frequency, and dead space-to-tidal volume ratio were identical between groups. As per the higher arterial Pco 2 of GED at V˙o 2 max, subjects with an exaggerated submaximal alveolar-arterial oxygen difference also showed a relative maximal hypoventilation. Results thus suggest the existence of a common denominator that contributes to the GED of submaximal exercise and affects the maximal ventilatory response. |
| Databáze: | OpenAIRE |
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