Bacterial co-infection at hospital admission in patients with COVID-19
| Autor: | Moreno García, Estela, Puerta Alcalde, Pedro, Letona Giménez, Laura, Meira, Fernanda, Dueñas, Gerard, Chumbita, Mariana, García Poutón, Nicole, Monzó, Patricia, Lopera, Carlos, Serra, Laia, Cardozo Espinola, Celia, Hernández-Meneses, Marta, Rico, Verónica, Bodro, Marta, Morata, Laura, Fernández Pittol, Mariana José, Grafia, Ignacio, Castro, Pedro, Mensa Pueyo, Josep, Martínez, José Antonio, Sanjuan, Gemma, Marcos, Ma. Angeles, Soriano Viladomiu, Alex, García Vidal, Carolina, Hospital Clinic of Barcelona COVID-19 Research Group |
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| Rok vydání: | 2021 |
| Předmět: |
Microbiology (medical)
Adult Malalts hospitalitzats Malalties bacterianes Coinfection SARS-CoV-2 Bacterial diseases COVID-19 Antibiòtics Coronavirus infections General Medicine Bacterial Infections Infeccions per coronavirus Hospital patients Hospitals Infectious Diseases Antibiotics Ferritins Humans Procalcitonin Retrospective Studies |
| Zdroj: | International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases. 118 |
| ISSN: | 1878-3511 |
| Popis: | Objectives: We described the current incidence and risk factors of bacterial co-infection in hospitalized patients with COVID-19. Methods: Observational cohort study was performed at the Hospital Clinic of Barcelona (February 2020-February 2021). All patients with COVID-19 who were admitted for >48 hours with microbiological sample collection and procalcitonin (PCT) determination within the first 48 hours were included. Results: A total of 1125 consecutive adults met inclusion criteria. Co-infections were microbiologically documented in 102 (9.1%) patients. Most frequent microorganisms were Streptococcus pneumoniae (79%), Staphylococcus aureus (6.8%), and Haemophilus influenzae (6.8%). Test positivity was 1% (8/803) for blood cultures, 10.1% (79/780) for pneumococcal urinary antigen test, and 11.4% (15/132) for sputum culture. Patients with PCT higher than 0.2, 0.5, 1, and 2 ng/mL had significantly more co-infections than those with lower levels (p=0.017, p=0.031, p94%. |
| Databáze: | OpenAIRE |
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