Development of a new tissue-equivalent material applied to optimizing surgical accuracy
| Autor: | Shan Jiang, Zhiliang Su, Yan Yu, Sha Liu, Xingji Wang |
|---|---|
| Rok vydání: | 2013 |
| Předmět: |
Vinyl alcohol
Kidney Cortex Materials science Sus scrofa Biocompatible Materials Bioengineering Hydrogel Polyethylene Glycol Dimethacrylate Biomaterials chemistry.chemical_compound Tensile Strength Materials Testing Animals Minimally Invasive Surgical Procedures Tissue Engineering integumentary system Phantoms Imaging Robotics Surgical training Solvent Tissue equivalent chemistry Mechanics of Materials Polyvinyl Alcohol Invasive surgery Stress Mechanical Biomedical engineering |
| Zdroj: | Materials Science and Engineering: C. 33:3768-3774 |
| ISSN: | 0928-4931 |
| DOI: | 10.1016/j.msec.2013.05.001 |
| Popis: | The precision of orientation to target placement during invasive therapy is mainly influenced by tool–tissue interaction. In this study, we aim to investigate a transparent Poly (vinyl alcohol) (PVA) hydrogel as tissue-equivalent material which is used in accurate surgical insertion research. The PVA hydrogel with specified formula was prepared by means of physical and chemical crosslink. The effects of chemical composition and synthesis technique on the biomechanical property, density and micro-structure morphology of PVA materials have been investigated in detail. It can be concluded that when PVA concentration is 8 g/dl, the NaCl concentration is 4 wt.%, with mix water/DMSO solvent, prepared under 7 freeze/thaw cycles, the material has the most similar properties with kidney tissue. Experimental results demonstrate that this tissue-equivalent material could be used in the ex vivo insertion accuracy test for robot-assisted percutaneous intervention and surgical training in minimally invasive surgery (MIS). |
| Databáze: | OpenAIRE |
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