Combined antithymocyte globulin cyclosporin methylprednisolone and granulocyte colony-stimulating factor are effective in a patient with hepatitis-associated severe aplastic anemia

Autor:	Masakazu Nitta, Hidetsugu Mihara, Hiroshi Miwa, Yoshiro Kato, Akira Imamura, Atsushi Sato, Emi Tajima, Akihito Hiramatsu, Minori Kanakura, Motohiro Wakabayashi
Rok vydání:	2002
Předmět:	Adult Male Globulin Methylprednisolone Severity of Illness Index Hepatitis Granulocyte Colony-Stimulating Factor Humans Medicine Antilymphocyte Serum biology business.industry Remission Induction Anemia Aplastic General Medicine medicine.disease Severe Aplastic Anemia Granulocyte colony-stimulating factor Acute Disease Immunology Cyclosporine biology.protein Drug Therapy Combination business Immunosuppressive Agents medicine.drug
Zdroj:	Nihon Naika Gakkai Zasshi. 91:1036-1038
ISSN:	1883-2083 0021-5384
DOI:	10.2169/naika.91.1036
Popis:	22歳,男性.発熱出現,急性肝炎(A, B, C, D, G陰性)と診断され補液により肝機能改善. HSV, CMV, EBV,パルボウイルス,風疹,麻疹抗体価の上昇認めず. WBC 1,400/μl, Hb 12.1g/dl, Plt 22,000/μlと汎血球減少悪化. methylprednisolone (m-PLS)大量療法では反応せず.肝炎後重症再生不良性貧血と診断. Antithymocyte globulin (ATG)・cyclosporin (CyA)・m-PSL・granulocyte colony-stimulating factor (G-CSF)併用療法を行い寛解を得た.現在治療薬なしで寛解を維持している.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a3c754a0ebf85369f9e667838219640e https://doi.org/10.2169/naika.91.1036 Zobrazit plný text záznamu