Correlation of MRI Visual Scales with Neuropsychological Profile in Mild Cognitive Impairment of Parkinson's Disease
| Autor: | Helenice Charchat-Fichman, Manuela Cruz, Denise Vieira Greca, João Santos Pereira, Luiz Felipe Rocha Vasconcellos, Mariana Spitz, Marcelo Adachi, Ana Lara Malak |
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| Jazyk: | angličtina |
| Rok vydání: | 2017 |
| Předmět: |
0301 basic medicine
medicine.medical_specialty Article Subject Trail Making Test Neuroscience (miscellaneous) Audiology behavioral disciplines and activities lcsh:RC346-429 03 medical and health sciences 0302 clinical medicine mental disorders medicine Memory span Dementia Verbal fluency test lcsh:Neurology. Diseases of the nervous system medicine.diagnostic_test business.industry Neuropsychology Montreal Cognitive Assessment Magnetic resonance imaging medicine.disease Psychiatry and Mental health 030104 developmental biology Neurology (clinical) business 030217 neurology & neurosurgery Stroop effect Research Article |
| Zdroj: | Parkinson's Disease Parkinson's Disease, Vol 2017 (2017) |
| ISSN: | 2042-0080 2090-8083 |
| Popis: | Few studies have evaluated magnetic resonance imaging (MRI) visual scales in Parkinson’s disease-Mild Cognitive Impairment (PD-MCI). We selected 79 PD patients and 92 controls (CO) to perform neurologic and neuropsychological evaluation. Brain MRI was performed to evaluate the following scales: Global Cortical Atrophy (GCA), Fazekas, and medial temporal atrophy (MTA). The analysis revealed that both PD groups (amnestic and nonamnestic) showed worse performance on several tests when compared to CO. Memory, executive function, and attention impairment were more severe in amnestic PD-MCI group. Overall analysis of frequency of MRI visual scales by MCI subtype did not reveal any statistically significant result. Statistically significant inverse correlation was observed between GCA scale and Mini-Mental Status Examination (MMSE), Montreal Cognitive Assessment (MoCA), semantic verbal fluency, Stroop test, figure memory test, trail making test (TMT) B, and Rey Auditory Verbal Learning Test (RAVLT). The MTA scale correlated with Stroop test and Fazekas scale with figure memory test, digit span, and Stroop test according to the subgroup evaluated. Visual scales by MRI in MCI should be evaluated by cognitive domain and might be more useful in more severely impaired MCI or dementia patients. |
| Databáze: | OpenAIRE |
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