Attenuated ANF Response to Exercise in Athletes with Exercise-Induced Hypoxemia
| Autor: | A Bonnardet, Patrick Mucci, I Couret, C. Préfaut, Fabienne Durand, Maurice Hayot |
|---|---|
| Rok vydání: | 2004 |
| Předmět: |
Adult
Male medicine.medical_specialty Rest Hemodynamics Physical Therapy Sports Therapy and Rehabilitation Physical exercise Incremental exercise Hypoxemia Atrial natriuretic peptide Heart Rate Reference Values Endurance training Internal medicine Heart rate medicine Humans Orthopedics and Sports Medicine Hypoxia Exercise business.industry Osmolar Concentration Sodium Blood Proteins Hypoxia (medical) Endocrinology Physical Endurance Potassium medicine.symptom business Atrial Natriuretic Factor |
| Zdroj: | International Journal of Sports Medicine. 25:252-256 |
| ISSN: | 1439-3964 0172-4622 |
| Popis: | Some highly trained endurance athletes develop an exercise-induced hypoxemia (EIH) at least partially due to a hemodynamic factor with a potential stress failure on pulmonary capillaries. Atrial natriuretic factor (ANF) is a pulmonary vasodilatator and its release during exercise could be reduced with endurance training. We hypothesized that athletes exhibiting EIH, who have a greater training volume than non-EIH athletes, have a reduced ANF release during exercise explaining the pathophysiology of EIH. Ten highly trained EIH-athletes (HT-EIH), ten without EIH (HT-nEIH), and nine untrained (UT) males performed incremental exercise to exhaustion. No between group differences occurred in resting ANF plasma levels. In contrast to HT-nEIH and UT (p < 0.05), HT-EIH showed a smaller increase in ANF concentration between rest and maximal exercise (HT-EIH: 8.12 +/- 0.69 vs. 14.1 +/- 1.86 pmol x l (-1); HT-nEIH: 10.46 +/- 1 vs. 18.7 +/- 1.8 pmol x l (-1); UT: 6.23 +/- 0.95 vs. 20.38 +/- 2.79 pmol x l (-1)). During the recovery, ANF levels decreased significantly in HT-nEIH and UT groups (p < 0.05). Electrolyte values increased in all groups during exercise but were higher in both trained groups. In conclusion, this study suggested that ANF response to exercise may be important for exercise-induced hypoxemia. |
| Databáze: | OpenAIRE |
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