Chromosome assignment of 115 expressed sequence tags (ESTs) from human skeletal muscle
| Autor: | Hoffman Eh, Natascia Tiso, G. Lanfranchi, Stephan D, Giorgio Valle, Gian Antonio Danieli, Teresa Muraro, Rosanna Zimbello |
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| Rok vydání: | 1997 |
| Předmět: |
Adult
DNA Complementary Skeletal muscle Gene Expression Rodentia Biology Hybrid Cells Chromosomes Cell Line Complementary DNA Genetics medicine Animals Humans Genomic library Muscle Skeletal Molecular Biology Gene Genetics (clinical) Gene mapping Expressed sequence tag Genomic Library cDNA library food and beverages Chromosome Chromosome Mapping medicine.anatomical_structure Expressed sequence tags Human genome Female |
| Zdroj: | Scopus-Elsevier Europe PubMed Central |
| ISSN: | 0301-0171 |
| Popis: | The chromosome assignment of 115 expressed sequence tags (ESTs) from human skeletal muscle, 101 of which identify unknown human genes, is reported. The ESTs were selected among over 4,000 obtained from systematic sequencing of a skeletal muscle cDNA library containing 3’ portions of the mRNAs. Chromosome assignments were ob tained by PCR amplification of two panels of human × rodent somatic cell hybrids. Analysis of these preliminary data suggests a nonrandom distribution of muscle ESTs in the human chromosome complement. The unexpected occurrence of multiple chromosome localizations for some ESTs is discussed. |
| Databáze: | OpenAIRE |
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