Long-term Chronological Changes in Very Asymmetric Keratoconus
| Autor: | Ryota Inoue, Vishal Jhanji, Shizuka Koh, Kazuichi Maruyama, Daijiro Kabata, Kohji Nishida, Naoyuki Maeda, Stephen D. Klyce, Ayumi Shintani |
|---|---|
| Rok vydání: | 2019 |
| Předmět: |
Adult
Male medicine.medical_specialty Keratoconus Younger age genetic structures Adolescent Corneal Pachymetry Scheimpflug principle Annual change Cornea 03 medical and health sciences Young Adult 0302 clinical medicine Ophthalmology Medicine Humans In patient Aged Retrospective Studies business.industry Astigmatism Corneal Topography Forme fruste Middle Aged medicine.disease University hospital Normal limit eye diseases ROC Curve 030221 ophthalmology & optometry Disease Progression Female sense organs business 030217 neurology & neurosurgery Tomography Optical Coherence |
| Zdroj: | Cornea. 38(5) |
| ISSN: | 1536-4798 |
| Popis: | PURPOSE To investigate chronological changes in patients with very asymmetric keratoconus (KC) by Scheimpflug-based corneal tomographic evaluation. METHODS We retrospectively reviewed the clinical records of 382 patients with KC attending a university hospital. Patients who were diagnosed with KC in one eye and forme fruste keratoconus in the other eye at the last visit and followed up with Scheimpflug-based tomographic corneal imaging were included. The anterior radius of curvature (ARC) and posterior radius of curvature (PRC) obtained at a 3.0-mm optical zone and the thinnest pachymetry reading of corneal thickness (Tmin), were used to investigate the chronological changes in tomographic parameters. RESULTS Twenty-six patients aged 16 to 66 years met the inclusion criteria. The mean observation period was 6 years and 4 months. There was a significant increase in annual change in PRC with a longer follow-up period after initial examination (P = 0.011). Moreover, a greater increase in annual change in ARC was observed in patients in whom the initial examination was performed at a younger age than in those in whom it was performed at an older age (P < 0.001). CONCLUSIONS On the basis of tomographic evaluation, even if the measured values are almost stable and within normal limits, a long-term clinical follow-up is warranted in forme fruste keratoconus eyes. Younger patients with very asymmetric keratoconus should be monitored carefully. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|