Evolución clínica y radiológica de una mujer con histiocitosis pulmonar de células de Langerhans durante 18 años
| Autor: | Paula Bustos B, Enrique Bellolio J, Miguel Villaseca H, Ximena Cea B |
|---|---|
| Rok vydání: | 2008 |
| Předmět: |
medicine.medical_specialty
Lung business.industry General Medicine Female adolescent neumotorax Pulmonary Langerhans cell histiocytosis medicine.disease Dermatology Pleuritic pain respiratory tract diseases Surgery Histiocitosis células de Langerhan medicine.anatomical_structure Pneumothorax Prednisone Bilateral pneumothorax Surgical biopsy Medicine business medicine.drug |
| Zdroj: | Revista chilena de enfermedades respiratorias v.24 n.2 2008 SciELO Chile CONICYT Chile instacron:CONICYT |
| ISSN: | 0717-7348 |
| DOI: | 10.4067/s0717-73482008000200009 |
| Popis: | The Pulmonary Langerhans cell histiocytosis (PLCH) is an uncommon pulmonary diffuse cystic disease. This review presents one case of PLCH diagnosed in a non-smoker female adolescent, who consulted for rapidly progressive dyspnea associated to left pleuritic pain that corresponded to a bilateral pneumothorax. The diagnosis was confirmed by surgical biopsy of the lung. Treatment with corticoids (prednisone) was indicated during the first year. After 18 years from diagnosis she presented an important clinical improvement, with a favourable but not complete radiological and spirometric improvement. The cases that make their debut with recurrent spontaneous pneumothorax are infrequent. The natural evolution of this disease is variable and the treatment is still controversial, been the immunosuppressive therapy, as corticoesteroids and cytotoxic agents of limited value, since are few studies that confirm their effectiveness |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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