The Multipartite Mitochondrial Genome of Enteromyxum leei (Myxozoa): Eight Fast-Evolving Megacircles
| Autor: | Dorothée Huchon, Arik Diamant, Dayana Yahalomi, Nimrod D. Rubinstein, Michal Haddas-Sasson, Tamar Feldstein |
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| Rok vydání: | 2017 |
| Předmět: |
0301 basic medicine
Mitochondrial DNA Molecular Sequence Data Biology Genome DNA Mitochondrial Chromosomes Evolution Molecular 03 medical and health sciences Genetics Animals Gene conversion Myxozoa Molecular Biology Gene Ecology Evolution Behavior and Systematics Phylogeny Base Sequence Circular bacterial chromosome Chromosome biology.organism_classification Mitochondria 030104 developmental biology Transfer RNA Genome Mitochondrial |
| Zdroj: | Molecular biology and evolution. 34(7) |
| ISSN: | 1537-1719 |
| Popis: | Myxozoans are a large group of poorly characterized cnidarian parasites. To gain further insight into their evolution, we sequenced the mitochondrial (mt) genome of Enteromyxum leei and reevaluate the mt genome structure of Kudoa iwatai. Although the typical animal mt genome is a compact, 13-25 kb, circular chromosome, the mt genome of E. leei was found to be fragmented into eight circular chromosomes of ∼23 kb, making it the largest described animal mt genome. Each chromosome was found to harbor a large noncoding region (∼15 kb), nearly identical between chromosomes. The protein coding genes show an unusually high rate of sequence evolution and possess little similarity to their cnidarian homologs. Only five protein coding genes could be identified and no tRNA genes. Surprisingly, the mt genome of K. iwatai was also found to be composed of two chromosomes. These observations confirm the remarkable plasticity of myxozoan mt genomes. |
| Databáze: | OpenAIRE |
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