[Perfusion, Metabolism and Regional Myocardial Contractility in Patients With Valvular Heart Disease: a Long-Term Follow-Up After Valve Replacement]
| Autor: | N V Mayorov, Lapekin Sv, A P Litvinov, Davydenko Vv, A A Pushkarev, Amosov Vi |
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| Rok vydání: | 2017 |
| Předmět: |
Hibernating myocardium
medicine.medical_specialty Heart disease business.industry medicine.medical_treatment valvular heart disease medicine.disease Intracardiac injection Contractility medicine.anatomical_structure Valve replacement Internal medicine cardiovascular system medicine Cardiology Heart valve medicine.symptom Cardiology and Cardiovascular Medicine business Perfusion |
| Zdroj: | Kardiologiia. 55(10) |
| ISSN: | 0022-9040 |
| Popis: | Aim To perform complex assessment of myocardial perfusion, metabolism, and regional contractility in patients with valvular heart disease (VHD) in remote period after surgical correction of heart defects. Material and methods We examined 30 patients with VHD in 1-8 years after heart valve replacement because of mitral (n=13) or aortic (n=17) valve defects of the following etiology: rheumatic heart disease (n=10), degeneration of connective tissue (n=13), infective endocarditis (n=7). For assessment of myocardial perfusion, metabolism, and regional contractility, we used single photon emission computed tomography (SPECT). Results Myocardium of patients who had undergone surgical correction of heart valve defects was characterized by dominating diffuse sclerotic changes localized mostly in basal segments. Hibernating myocardium was a less frequent finding. There were segments of borderline state with normal parameters of metabolism but slight impairment of perfusion without pronounced disturbances of kinetics. Patients with infectious etiology of valvular defects had combined perfusion and metabolic changes in multiple myocardial segments. Extensive derangements of perfusion and metabolism were characteristic for patients with connective tissue degeneration. Conclusion Signs of cardiac failure caused by disturbances of myocardial perfusion and metabolism in patients with valvular heart disease can persist even after successful correction of valvular defect with normalization of intracardiac hemodynamics. |
| Databáze: | OpenAIRE |
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