Scintigraphic evaluation of gallbladder motor functions in H pylori positive and negative patients in the stomach with dyspepsia
Autor: | Olga Yaylali, Fatma Suna Kiraç, Mustafa Tahsin Yilmaz, Serkan Degirmencioglu, Metin Akbulut |
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Rok vydání: | 2008 |
Předmět: |
Male
gallbladder scintiscanning gastrointestinal endoscopy Technetium Gastroenterology Urea Carbon Radioisotopes gallbladder emptying Ejection fraction H pylori biology medicine.diagnostic_test Stomach digestive oral and skin physiology mebrofenin tc 99m article Gallbladder General Medicine Middle Aged female medicine.anatomical_structure Breath Tests Cholescintigraphy histopathology Female Rapid Communication Adult medicine.medical_specialty Urea breath test gallbladder motility Stomach Diseases chemistry.chemical_element dyspepsia Sensitivity and Specificity Helicobacter infection Helicobacter Infections urea breath test Internal medicine medicine Humans controlled study human Dyspepsia Radionuclide Imaging reliability Helicobacter pylori Gastric emptying business.industry echography 14C-urea breath test bacterial infections and mycoses biology.organism_classification major clinical study bile composition Gastric Emptying chemistry Case-Control Studies business |
Zdroj: | World Journal of Gastroenterology. 14:1406 |
ISSN: | 1007-9327 |
DOI: | 10.3748/wjg.14.1406 |
Popis: | Aim: To evaluate the relationship between gallbladder (GB) motor function and H pylori infection in the stomach. Methods: All cases (86) underwent the 14C urea breath test (UBT). 14C-UBT was found as positive in 58 and negative in 28 dyspeptic patients. 14C- UBT was accepted as a gold standard test. Clo test and histopathologic examination were compared with the results of 14C-UBT in cases who tolerated upper gastrointestinal endoscopy procedure. Cholescintigraphy with 99mTc-mebrofenin was used to determine the parameters of GB motor function (GB filling and emptying time, half of the emptying time, ejection fraction at 30th and 60th min) in all patients. Results: We found the sensitivity and specificity as 88% and 86% for Clo test and as 89% and 80% for histologic evaluation, respectively. The parameters of GB function were not significantly different in H pylori positive and negative patients. The GB emptying was normal in both groups. Minimum GB filling time was 30 min in 34 of 86 cases (39.5%), filling was not observed in 2 cases. The GB ultrasonography (USG) results were normal for all cases and bile composition abnormality was not determined. Conclusion: Our study showed that 14C-UBT is highly reliable method to detect the presence of H pylori. The presence of H pylori infection does not directly affect the GB function. © 2008 WJG. All rights reserved. |
Databáze: | OpenAIRE |
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