Scintigraphic evaluation of gallbladder motor functions in H pylori positive and negative patients in the stomach with dyspepsia

Autor: Olga Yaylali, Fatma Suna Kiraç, Mustafa Tahsin Yilmaz, Serkan Degirmencioglu, Metin Akbulut
Rok vydání: 2008
Předmět:
Male
gallbladder scintiscanning
gastrointestinal endoscopy
Technetium
Gastroenterology
Urea
Carbon Radioisotopes
gallbladder emptying
Ejection fraction
H pylori
biology
medicine.diagnostic_test
Stomach
digestive
oral
and skin physiology

mebrofenin tc 99m
article
Gallbladder
General Medicine
Middle Aged
female
medicine.anatomical_structure
Breath Tests
Cholescintigraphy
histopathology
Female
Rapid Communication
Adult
medicine.medical_specialty
Urea breath test
gallbladder motility
Stomach Diseases
chemistry.chemical_element
dyspepsia
Sensitivity and Specificity
Helicobacter infection
Helicobacter Infections
urea breath test
Internal medicine
medicine
Humans
controlled study
human
Dyspepsia
Radionuclide Imaging
reliability
Helicobacter pylori
Gastric emptying
business.industry
echography
14C-urea breath test
bacterial infections and mycoses
biology.organism_classification
major clinical study
bile composition
Gastric Emptying
chemistry
Case-Control Studies
business
Zdroj: World Journal of Gastroenterology. 14:1406
ISSN: 1007-9327
DOI: 10.3748/wjg.14.1406
Popis: Aim: To evaluate the relationship between gallbladder (GB) motor function and H pylori infection in the stomach. Methods: All cases (86) underwent the 14C urea breath test (UBT). 14C-UBT was found as positive in 58 and negative in 28 dyspeptic patients. 14C- UBT was accepted as a gold standard test. Clo test and histopathologic examination were compared with the results of 14C-UBT in cases who tolerated upper gastrointestinal endoscopy procedure. Cholescintigraphy with 99mTc-mebrofenin was used to determine the parameters of GB motor function (GB filling and emptying time, half of the emptying time, ejection fraction at 30th and 60th min) in all patients. Results: We found the sensitivity and specificity as 88% and 86% for Clo test and as 89% and 80% for histologic evaluation, respectively. The parameters of GB function were not significantly different in H pylori positive and negative patients. The GB emptying was normal in both groups. Minimum GB filling time was 30 min in 34 of 86 cases (39.5%), filling was not observed in 2 cases. The GB ultrasonography (USG) results were normal for all cases and bile composition abnormality was not determined. Conclusion: Our study showed that 14C-UBT is highly reliable method to detect the presence of H pylori. The presence of H pylori infection does not directly affect the GB function. © 2008 WJG. All rights reserved.
Databáze: OpenAIRE