A REVIEW ON CORRELATION BETWEEN LIPID PROFILE AND DEPRESSION
Autor: | Muthiah Nagasundaram, Satya Narayana Murthy Kasturi, Lalitha Devi Dhulipala |
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Rok vydání: | 2016 |
Předmět: |
medicine.medical_specialty
Low Cholesterol medicine.diagnostic_test Depression lcsh:R5-130.5 business.industry Lipids Correlation Endocrinology Self-harm Internal medicine Medicine lipids (amino acids peptides and proteins) business Lipid profile lcsh:General works Depression (differential diagnoses) |
Zdroj: | Journal of Evidence Based Medicine and Healthcare, Vol 3, Iss 59, Pp 3220-3224 (2016) |
ISSN: | 2349-2570 2349-2562 |
DOI: | 10.18410/jebmh/2016/697 |
Popis: | Epidemiological and clinical intervention data indicate that low levels of circulating lipids and cholesterol are the risk factors for depressive symptoms. Olie et al 2011 (1) showed an association of low cholesterol and self-harm in their study. In the present scenario, depression and anxiety disorders have high prevalence rates and are frequently related. Understanding the subject and concepts/mechanisms related to neurobiological basis for these disorders is very important and the available techniques or methods are ineffective. Lipids generally play an important role in neural function in the brain. The composition of lipid of the brain influences perception, mood and behaviour. Lipids are responsible to regulate the membrane's function which acts as a barrier between the intracellular and extracellular spaces. It is found that membrane lipids determine the local behaviour and characterisation and function of proteins within the membrane. It is found from the literature that lipids can influence both exo-and endocytic processes and work within the membrane as second messengers. This paper discusses some important case studies related to the correlation between lipid profile and the depression. |
Databáze: | OpenAIRE |
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