Diffuse leiomyomatosis with circumferential thickening of the gastrointestinal wall, resembling human diffuse leiomyomatosis, in a young miniature dachshund
| Autor: | Takeshi Izawa, Terumasa Shimada, Mitsuru Kuwamura, Mutsuki Mori, Jyoji Yamate, Shunsuke Shimamura, Mizuki Kuramochi |
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| Rok vydání: | 2020 |
| Předmět: |
Pathology
medicine.medical_specialty 040301 veterinary sciences Dachshund gastroesophageal junction Aspiration pneumonia Diffuse leiomyomatosis Esophageal Diseases Pneumonia Aspiration anorectal junction 0403 veterinary science 03 medical and health sciences Dogs Leiomyomatosis leiomyoma Animals Medicine Dog Diseases Gastrointestinal wall Gastrointestinal Neoplasms 030304 developmental biology 0303 health sciences Gastrointestinal tract General Veterinary business.industry Rectal Prolapse 04 agricultural and veterinary sciences Note medicine.disease Actins Rectal prolapse Rectal Diseases Leiomyoma medicine.anatomical_structure Female Esophagogastric Junction gastrointestinal tract Thickening business |
| Zdroj: | The Journal of Veterinary Medical Science |
| ISSN: | 1347-7439 0916-7250 |
| DOI: | 10.1292/jvms.19-0453 |
| Popis: | Leiomyoma is the most common mesenchymal tumor in the gastrointestinal (GI) tract. Leiomyomas usually have a single or multinodular mass of various sizes, and affected animals can develop alimentary symptoms depending on the location and size. A 3-year old female miniature dachshund died after a history of refractory rectal prolapse, esophagectasis and aspiration pneumonia. At necropsy, the GI wall at the gastroesophageal and anorectal junctions was circumferentially thickened. Histologically, both GI lesions were composed of bundles of well-differentiated smooth muscles without mass formation or invasive growth. The neoplastic cells had little cellular atypia and low proliferative activity, and were positive for α-smooth muscle actin. The lesions were diagnosed as diffuse leiomyomatosis with circumferential thickening of the GI wall and has not been described in the veterinary literature. |
| Databáze: | OpenAIRE |
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