| Autor: |
Adrian Hall, Jan Abendroth, Madison J. Bolejack, Tom Ceska, Sylvie Dell’Aiera, Victoria Ellis, David Fox, Cyril François, Muigai M. Muruthi, Camille Prével, Karine Poullennec, Sergei Romanov, Anne Valade, Alain Vanbellinghen, Jason Yano, Martine Geraerts |
| Rok vydání: |
2022 |
| Předmět: |
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| Zdroj: |
ACS Medicinal Chemistry Letters. 13:1099-1108 |
| ISSN: |
1948-5875 |
| DOI: |
10.1021/acsmedchemlett.2c00134 |
| Popis: |
We describe the identification and characterization of a series of covalent inhibitors of the C-terminal kinase domain (CTKD) of MSK1. The initial hit was identified via a high-throughput screening and represents a rare example of a covalent inhibitor which acts via an S |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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