Are Muscle Relaxants Needed for Nasal Intubation in Propofol and Remifentanil Anesthesia?
| Autor: | Katsuhisa Sunada, Naohiko Katsuyama, Masatoshi Ide |
|---|---|
| Rok vydání: | 2014 |
| Předmět: |
medicine.medical_specialty
medicine.drug_class medicine.medical_treatment Remifentanil Nose Double-Blind Method Piperidines medicine Humans Intubation Rocuronium Propofol Saline Muscle Relaxants Central business.industry Muscle relaxant Surgery medicine.anatomical_structure Otorhinolaryngology Anesthesia Cuff Oral Surgery business Anesthetics Intravenous medicine.drug |
| Zdroj: | Journal of Oral and Maxillofacial Surgery. 72:2134-2139 |
| ISSN: | 0278-2391 |
| DOI: | 10.1016/j.joms.2014.07.020 |
| Popis: | Purpose The authors hypothesized that a muscle relaxant would have no meaningful difference in intubation conditions during nasal intubation under remifentanil and propofol anesthesia. Materials and Methods This parallel-group, double-blinded, randomized controlled trial included 44 patients who received saline (S group; n = 22) or rocuronium (R group; n = 22). In addition to remifentanil 0.5 μg/kg per minute and propofol 5 mg/kg per hour, propofol 0.5 mg/kg was administered until loss of consciousness. Nasal intubation was performed 10 minutes after administration of R or S 0.6 mg/kg. Significant differences in intubation conditions and salivary amylase levels before and after intubation were tested (P Results Vocal cord status (P = .003) and response to intubation or cuff filling (P = .008) were significantly different, but intubation conditions were not. Salivary amylase level was significantly lower with R administration (P = .022). No patient complained of postoperative throat pain and hoarseness. Conclusion Muscle relaxants during nasal intubation performed after bolus administration of propofol 0.9 mg/kg in addition to 10 minutes of remifentanil 0.5 μg/kg per minute plus propofol 5 mg/kg per hour are unnecessary. |
| Databáze: | OpenAIRE |
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