Prognostic Impact of Coronary Flow Reserve in Patients With Reduced Left Ventricular Ejection Fraction

Autor: Hyun Sung Joh, Doosup Shin, Joo Myung Lee, Seung Hun Lee, David Hong, Ki Hong Choi, Doyeon Hwang, Coen K. M. Boerhout, Guus A. de Waard, Ji‐Hyun Jung, Hernan Mejia‐Renteria, Masahiro Hoshino, Mauro Echavarria‐Pinto, Martijn Meuwissen, Hitoshi Matsuo, Maribel Madera‐Cambero, Ashkan Eftekhari, Mohamed A. Effat, Tadashi Murai, Koen Marques, Joon‐Hyung Doh, Evald H. Christiansen, Rupak Banerjee, Hyun Kuk Kim, Chang‐Wook Nam, Giampaolo Niccoli, Masafumi Nakayama, Nobuhiro Tanaka, Eun‐Seok Shin, Steven A. J. Chamuleau, Niels van Royen, Paul Knaapen, Bon Kwon Koo, Tsunekazu Kakuta, Javier Escaned, Jan J. Piek, Tim P. van de Hoef, Mohamed AEffat, Niels Royen
Přispěvatelé: Cardiology, ACS - Atherosclerosis & ischemic syndromes, ACS - Heart failure & arrhythmias, Graduate School, 03 Heart Centre, Amsterdam Cardiovascular Sciences
Rok vydání: 2022
Předmět:
Zdroj: Joh, H S, Shin, D, Lee, J M, Lee, S H, Hong, D, Choi, K H, Hwang, D, Boerhout, C K M, de Waard, G A, Jung, J-H, Mejia-Renteria, H, Hoshino, M, Echavarria-Pinto, M, Meuwissen, M, Matsuo, H, Madera-Cambero, M, Eftekhari, A, Effat, M A, Murai, T, Marques, K, Doh, J-H, Christiansen, E H, Banerjee, R, Kim, H K, Nam, C-W, Niccoli, G, Nakayama, M, Tanaka, N, Shin, E-S, Chamuleau, S A J, van Royen, N, Knaapen, P, Koo, B K, Kakuta, T, Escaned, J, Piek, J J, van de Hoef, T P & ILIAS Registry Investigators [Link] 2022, ' Prognostic Impact of Coronary Flow Reserve in Patients With Reduced Left Ventricular Ejection Fraction ', Journal of the American Heart Association, vol. 11, no. 15, e025841 . https://doi.org/10.1161/JAHA.122.025841
Journal of the American Heart Association, 11(15):e025841. Wiley-Blackwell
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 11
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 11, 15
ILIAS Registry Investigators [Link] 2022, ' Prognostic Impact of Coronary Flow Reserve in Patients With Reduced Left Ventricular Ejection Fraction ', Journal of the American Heart Association, vol. 11, no. 15, e025841, pp. e025841 . https://doi.org/10.1161/JAHA.122.025841
ISSN: 2047-9980
DOI: 10.1161/JAHA.122.025841
Popis: Background Intracoronary physiologic indexes such as coronary flow reserve (CFR) and left ventricular ejection fraction (LVEF) have been regarded as prognostic indicators in patients with coronary artery disease. The current study evaluated the association between intracoronary physiologic indexes and LVEF and their differential prognostic implications in patients with coronary artery disease. Methods and Results A total of 1889 patients with 2492 vessels with available CFR and LVEF were selected from an international multicenter prospective registry. Baseline physiologic indexes were measured by thermodilution or Doppler methods and LVEF was recorded at the index procedure. The primary outcome was target vessel failure, which was a composite of cardiac death, target vessel myocardial infarction, or clinically driven target vessel revascularization over 5 years of follow‐up. Patients with reduced LVEF P P Conclusions CFR was lower in patients with reduced LVEF because of increased resting coronary flow. Patients with reduced CFR showed a significantly higher risk of target vessel failure than did those with preserved CFR, regardless of LVEF. Registration URL: https://www.clinicaltrials.gov ; Unique identifier: NCT04485234.
Databáze: OpenAIRE
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