Cystic fibrosis-related diabetes
Autor: | Erin Booth |
---|---|
Rok vydání: | 2011 |
Předmět: |
Male
Pediatrics medicine.medical_specialty Adolescent Cystic Fibrosis Cystic fibrosis-related diabetes Population Disease Comorbidity Cystic fibrosis Nurse's Role Risk Assessment Severity of Illness Index medicine Prevalence Humans education Child Depression (differential diagnoses) Monitoring Physiologic Patient Care Team education.field_of_study business.industry Incidence (epidemiology) medicine.disease Prognosis Combined Modality Therapy Pediatric Nursing Diabetes Mellitus Type 1 Treatment Outcome Child Preschool Life expectancy Female business |
Zdroj: | Journal of pediatric nursing. 26(6) |
ISSN: | 1532-8449 |
Popis: | Cystic fibrosis (CF) is the most common life-threatening autosomal recessive genetic disease in the United States with an incidence of 1 in 3,500 live births. According to the Cystic Fibrosis Foundation's (CFF) patient registry, approximately 30,000 children and adults in the United States are affected. In the 1950s, a diagnosis of CF resulted in a life expectancy of only 15 years; however, with advances in medical and nutritional management, life expectancy has improved significantly. The CFF now reports a life expectancy of 37.4 years. In addition, more than 45% of patients living with CF are older than 18 years. Improved life expectancy is a positive outcome, although it has led to a need to address previously overlooked complications and comorbities. Infertility, bone disease, depression, glucose intolerance, and CF-related diabetes (CFRD) have all become integral pieces to successful management of the aging CF population (CFF, 2009). CFRD is a serious and the most common comorbidity occurring in approximately 20% of adolescents and 40%– 50% of adults (Moran, Dunitz, Saeed, Holme, & Thomas, 2009). Although the prevalence varies depending on screening and diagnostic criteria used, it is suggested that more than 50% of persons with CF older than 30 years have CFRD (O'Riordan, Robinson, Donaghue, & Moran, 2008). The significance of CFRD cannot be disregarded. CFRD can lead to decreased lung function, poor nutritional status, and decreased survival rates. Early diagnosis is critical because clinical deterioration begins 6–24 months prior to diagnosis. |
Databáze: | OpenAIRE |
Externí odkaz: |