An accuate method for measurement of aldosterone production
| Autor: | J. P. Thomas, R. J. Oake |
|---|---|
| Rok vydání: | 1969 |
| Předmět: |
History
medicine.medical_specialty Aldosterone Daily production Daily intake Chromatography Paper Metabolite Sodium Articles Tritium Computer Science Applications Education Diet chemistry.chemical_compound Endocrinology chemistry Internal medicine medicine Methods Humans Aldosterone excretion Hospital patients Chromatography Thin Layer Production rate |
| Zdroj: | The Biochemical journal. 115(1) |
| ISSN: | 0264-6021 |
| Popis: | A method is described for isolation of the acid-hydrolysable metabolite of aldosterone in sufficient purity to measure accurately the daily production rate. Values obtained with six hospital patients were 84–131μg./day on a daily intake of 100m-equiv. of Na+ and 227–464μg./day on a daily intake of 10m-equiv. of Na+. Corresponding values for aldosterone excretion were also recorded, but these are a poor index of production rate since they represent from 1·6 to 9·8% of the total daily output of aldosterone. |
| Databáze: | OpenAIRE |
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