Enhanced detection of normal retinal nerve-fiber striations using a charge-coupled device and digital filtering

Autor: Qian Wei, David W. Richards, R.P. Velthuizen, James R. Janesick, Arsham Dingizian, S. Thomas Elliot, Laurence P. Clarke
Rok vydání: 1993
Předmět:
Zdroj: Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie. 231(10)
ISSN: 0721-832X
Popis: We used a 1024 x 1024 pixel, 15-microns, 16-bit-encoding, multi-pin-phase charge-coupled device (CCD) to obtain images of the normal human retinal nerve fiber layer. This device, which operates at room temperature, offers significantly better signal-to-noise ratio, linearity, and dynamic range than do photographic film, video imaging techniques, or commercially available CCDs. We demonstrate the use of a nonlinear digital filter, together with filter windows, that enhances fine detail of NFL striations, while suppressing noise, in limited areas of the CCD images. High-sensitivity imaging of this type, together with appropriate digital processing, may prove useful in diagnosing and following nerve-fiber-layer damage due to glaucoma.
Databáze: OpenAIRE