Frequency of sensitization to the individual fragrances of fragrance mix I and II according to the factors included in the MOAHLFA index

Autor:	Paloma Sánchez-Pedreño, Ana Giménez-Arnau, Felipe Heras-Mendaza, Leopoldo Borrego, Jose M. Carrascosa, R. González-Pérez, J.C. Armario-Hita, María E. Gatica-Ortega, Begoña García-Bravo, Juan García-Gavín, María A Pastor-Nieto, Susana Córdoba, I. Ruiz-Gonzalez, Tatiana Sanz-Sánchez, Pedro Mercader, Javier Ortiz de Frutos, Javier Sánchez-Pérez, Esther Serra, J.F. Silvestre, Virginia Fernández-Redondo, María José Sánchez-Pujol, Violeta Zaragoza, Alexandre Docampo-Simón, Marcos Hervella-Garcés
Rok vydání:	2021
Předmět:	Adult Male medicine.medical_specialty Occupational Dermatitis Epidemiology MOAHLFA index Population Dermatology Hand Dermatoses Leg Dermatoses Patch test Dermatitis Atopic 030207 dermatology & venereal diseases 03 medical and health sciences 0302 clinical medicine medicine Immunology and Allergy Humans 030212 general & internal medicine Age of Onset education Child Allergic contact dermatitis Sensitization Retrospective Studies education.field_of_study business.industry Atopic dermatitis Patch Tests medicine.disease medicine.anatomical_structure fragrances Dermatitis Occupational Spain Dermatitis Allergic Contact Odorants epidemiology Body region Female allergic contact dermatitis business Fragrances patch test Facial Dermatoses
Zdroj:	CONTACT DERMATITIS r-IIB SANT PAU. Repositorio Institucional de Producción Científica del Instituto de Investigación Biomédica Sant Pau instname r-ISABIAL. Repositorio Institucional de Producción Científica del Instituto de Investigación Biomédica y Sanitaria de Alicante Contact Dermatitis r-IGTP. Repositorio Institucional de Producción Científica del Instituto de Investigación Germans Trias i Pujol
ISSN:	1600-0536 0105-1873
Popis:	Background: Fragrances constitute the second most frequent cause of allergic contact dermatitis in Spain. Objectives: To determine the rate of sensitization to the individual fragrances of fragrance mix (FM) I and FM II for each of the demographic and clinical factors included in the MOAHLFA (male, occupational dermatitis, atopic dermatitis, hand dermatitis, leg dermatitis, facial dermatitis, age) index. Methods: We conducted a 5-year retrospective study in 23 Spanish centres. We identified the patients who had undergone patch testing with a specific fragrance series after reacting positively to fragrance markers in a baseline series. We obtained the MOAHLFA index items in this population, then calculated for each demographic and clinical factor the frequencies of sensitization to the individual fragrances of FM I and FM II. Results: A specific fragrance series was patch tested in 1013 patients. The most frequent allergens in men, women, children, and retired people were Evernia prunastri (16%), geraniol (16.6%), isoeugenol (17.9%), and geraniol (22.4%), respectively. Citral (20.5%) and hydroxyisohexyl 3-cyclohexene carboxaldehyde (HICC) (14.5%) were the most common allergens in occupational eczemas and were also associated with a large proportion of hand and facial dermatitis. Conclusions: Frequency of sensitization to the individual fragrances of FM I and FM II varies with age, sex, affected body region, and history of occupational or atopic dermatitis.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a3860a71f552ffa55e330c09b55240ea https://pubmed.ncbi.nlm.nih.gov/33534191 Zobrazit plný text záznamu Plný text ve formátu PDF Plný text ve formátu HTML
Nepřihlášeným uživatelům se plný text nezobrazuje	K zobrazení výsledku je třeba se přihlásit.