Mast cells in the placenta. Is there a relation to the development of atopic disease in infants before 18 months of age?

Autor: Lise Grupe Larsen, Christine Felding, Birthe Andersen, Pia Sander, Anne Lis Mikkelsen
Rok vydání: 1994
Předmět:
Zdroj: jpme. 22:273-278
ISSN: 1619-3997
0300-5577
DOI: 10.1515/jpme.1994.22.4.273
Popis: OBJECTIVE To disclose a relation between the amount of mast cells in placenta and the development of atopic disease in children before 18 months of age. DESIGN A prospective, descriptive study. SETTING Two obstetric departments at university hospitals. SUBJECTS 67 pairs of mothers and their newborn infants. MAIN OUTCOME MEASURES Family history of atopic disease was taken. The amount of mast cells in placenta was counted. Follow-up questionnaires of the children were evaluated after 18 months. RESULTS The follow-up rate was 84%. The number of mast cells in placenta did not differ between atopic and non-atopic children. CONCLUSION A new predictor, the amount of mast cells in placenta was evaluated. In this study the amount of mast cells, in placenta was not predictive of the development of atopic disease before 18 months of age.
Databáze: OpenAIRE