Mortality of bullous pemphigoid: An evaluation of 223 patients and comparison with the mortality in the general population in the United States
| Autor: | Zongqi Xia, Neil J. Korman, Sue Manos, Senait W Dyson, Stacey Brisman, Sareeta Parker, Robert A. Swerlick, Rizwana Khan, Michelle L. Pennie, Benjamin D. Korman |
|---|---|
| Rok vydání: | 2008 |
| Předmět: |
Adult
Male medicine.medical_specialty Population Dermatology Cohort Studies Age Distribution Cause of Death Internal medicine Immunopathology Pemphigoid Bullous Epidemiology Confidence Intervals Humans Medicine Sex Distribution education Aged Retrospective Studies Aged 80 and over education.field_of_study business.industry Retrospective cohort study Middle Aged medicine.disease Control subjects United States Confidence interval Surgery Survival Rate Standardized mortality ratio Case-Control Studies Female Bullous pemphigoid business |
| Zdroj: | Journal of the American Academy of Dermatology. 59:582-588 |
| ISSN: | 0190-9622 |
| DOI: | 10.1016/j.jaad.2008.07.022 |
| Popis: | Background There are large discrepancies in reported mortality for bullous pemphigoid (BP). Objective We sought to determine the mortality of a large cohort of patients with BP and compare this with age-matched control subjects. Methods Data were collected on 223 patients with a new diagnosis of BP between 1998 and 2003 through our cutaneous immunofluorescence laboratory databases. The mortality of patients with BP was compared with that of age-matched control subjects in the general US population. Results The 1-, 2-, and 5-year mortality was 0.23 (95% confidence interval=0.18, 0.29), 0.37 (95% confidence interval=0.31, 0.44), and 0.50 (95% confidence interval=0.42, 0.57), respectively. However, relative to age-matched control subjects, no difference in expected mortality was detected. Limitations This was a retrospective cohort analysis. Conclusions Mortality of patients with BP is more likely related to advanced age and associated medical conditions than to disease-specific factors. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|
Full Text from ScienceDirect