Hepatic resection for breast cancer metastases
Autor: | M. W. Kissin, D. J. Durkin, N. D. Karanjia, A. C. Okaro, G. T. Layer |
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Rok vydání: | 2005 |
Předmět: |
Adult
medicine.medical_specialty Colorectal cancer Hepatic resection medicine.medical_treatment Breast Neoplasms Breast cancer Hepatectomy Humans Medicine Effective treatment Prospective Studies Prospective cohort study Survival analysis business.industry Liver Neoplasms General Medicine Middle Aged medicine.disease Survival Analysis Surgery Treatment Outcome Female business Median survival Research Article |
Zdroj: | Annals of The Royal College of Surgeons of England. 87:167-170 |
ISSN: | 1478-7083 0035-8843 |
Popis: | INTRODUCTION: Hepatic resection is an established modality of treatment for colorectal cancer metastases. Resection of breast cancer liver metastases remains controversial, but has been shown to be an effective treatment in selected cases. This study reports the outcome of 8 patients with liver metastases from breast cancer. PATIENTS & METHODS: 8 patients with liver metastases from previously treated breast cancer were referred for hepatic resection between September 1996 and December 2002. Six were eligible for liver resection. The mean age was 45.8 years. The resections performed included 1 segmentectomy and 5 hemihepatectomies of which one was an extended hemihepatectomy. One patient had a repeat hepatectomy 44 months after the first resection. RESULTS: There were no postoperative deaths or major morbidity. The resectability rate was 75%. Follow-up periods range from 6 to 70 months with a median survival of 31 months following resection. There have been 2 deaths, one died of recurrence in the residual liver at 6 months and one died disease-free from a stroke. Of the remaining 4 patients, 1 has had a further liver resection at 44 months following which she is alive and 'disease-free' at 70 months. The one patient with peritoneal recurrence is alive 49 months after her liver resection with 2 patients remaining disease-free. CONCLUSION: Hepatic resection for breast cancer liver metastases is a safe procedure with low morbidity and mortality. |
Databáze: | OpenAIRE |
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