Plasma levels of mid-regional pro-adrenomedullin in sepsis are associated with risk of death
| Autor: | María Ángela González-García, J. F. Rodríguez-Gutiérrez, Jordi Rello, Francisco Valenzuela-Sánchez, Rafael Bohollo de Austria, Laura Fernández-Ruiz, Blanca Valenzuela-Méndez, Ángel Estella-García |
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| Rok vydání: | 2018 |
| Předmět: |
Male
medicine.medical_specialty Risk Assessment Severity of Illness Index Procalcitonin law.invention Sepsis 03 medical and health sciences Adrenomedullin 0302 clinical medicine 030202 anesthesiology law Internal medicine Cause of Death Epidemiology Severity of illness medicine Humans Prospective Studies Prospective cohort study Cause of death Aged business.industry Organ dysfunction 030208 emergency & critical care medicine Middle Aged medicine.disease Prognosis Intensive care unit Anesthesiology and Pain Medicine Female medicine.symptom business |
| Zdroj: | Minerva anestesiologica. 85(4) |
| ISSN: | 1827-1596 |
| Popis: | BACKGROUND Identifying Intensive Care Unit (ICU) patients with sepsis and predicting the risk of death are unmet clinical needs. METHODS Prospective observational single-center study of 120 consecutive ICU patients with suspected severe sepsis at Jerez Hospital. Epidemiological, clinical, laboratory data and MR-proADM, Procalcitonin (PCT) and C-reactive protein (CRP) levels were recorded at ICU admission and follow-up. RESULTS At ICU discharge, 104 patients were diagnosed with severe sepsis and 39 died. Plasma MR-proADM was highly indicative of sepsis: 4.05 nmol/L vs. of 0.309 nmol/L (P |
| Databáze: | OpenAIRE |
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