Automated 3D Fetal Brain Segmentation Using an Optimized Deep Learning Approach

Autor: L. Zhao, J.D. Asis-Cruz, X. Feng, Y. Wu, K. Kapse, A. Largent, J. Quistorff, C. Lopez, D. Wu, K. Qing, C. Meyer, C. Limperopoulos
Rok vydání: 2022
Předmět:
Zdroj: AJNR Am J Neuroradiol
ISSN: 1936-959X
0195-6108
DOI: 10.3174/ajnr.a7419
Popis: BACKGROUND AND PURPOSE: MR imaging provides critical information about fetal brain growth and development. Currently, morphologic analysis primarily relies on manual segmentation, which is time-intensive and has limited repeatability. This work aimed to develop a deep learning–based automatic fetal brain segmentation method that provides improved accuracy and robustness compared with atlas-based methods. MATERIALS AND METHODS: A total of 106 fetal MR imaging studies were acquired prospectively from fetuses between 23 and 39 weeks of gestation. We trained a deep learning model on the MR imaging scans of 65 healthy fetuses and compared its performance with a 4D atlas-based segmentation method using the Wilcoxon signed-rank test. The trained model was also evaluated on data from 41 fetuses diagnosed with congenital heart disease. RESULTS: The proposed method showed high consistency with the manual segmentation, with an average Dice score of 0.897. It also demonstrated significantly improved performance (P
Databáze: OpenAIRE