Combination of a normal D-dimer concentration and a non-high pretest clinical probability score is a safe strategy to exclude deep venous thrombosis
| Autor: | Fred J. L. M. Haas, H. K. Nieuwenhuis, R. Oltmans, Henny G. Peltenburg, Roger E. G. Schutgens, A.H. Pijlman, P. Ackermark, Menno Pruijm, Douwe H. Biesma, J.C. Kelder |
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| Rok vydání: | 2003 |
| Předmět: |
Male
medicine.medical_specialty Deep vein Diagnostic Techniques Cardiovascular Fibrinogen Sensitivity and Specificity Fibrin Cohort Studies Diagnosis Differential Fibrin Fibrinogen Degradation Products Predictive Value of Tests Physiology (medical) D-dimer Outpatients medicine Humans Prospective Studies Ultrasonography Venous Thrombosis Leg biology Vascular disease business.industry Safe strategy Middle Aged medicine.disease Thrombosis Surgery Venous thrombosis medicine.anatomical_structure biology.protein Female Radiology Cardiology and Cardiovascular Medicine business Pulmonary Embolism medicine.drug Follow-Up Studies |
| Zdroj: | Circulation. 107(4) |
| ISSN: | 1524-4539 |
| Popis: | Background— Serial ultrasonography is reliable for the diagnosis of deep venous thrombosis in symptomatic patients, but the low prevalence of thrombosis in this group renders the approach costly and inconvenient to patients. We studied the clinical validity of the combination of a pretest clinical probability score and a D-dimer test in the initial evaluation of patients suspected of deep venous thrombosis. Methods and Results— Patients with a normal D-dimer concentration ( Conclusion— The combination of a non-high pretest clinical probability score and a normal D-dimer concentration is a safe strategy to rule out deep venous thrombosis and to withhold anticoagulation. |
| Databáze: | OpenAIRE |
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