Serum vitamin D concentrations in young Turkish women with primary dysmenorrhea: A randomized controlled study
| Autor: | Ilknur Mutlu, Fatih Çelik, Osman Karacin, Mine Kanat-Pektas, Mehmet Yilmazer, Mesut Köse |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2018 |
| Předmět: |
Adult
medicine.medical_specialty Adolescent Turkey Visual analogue scale Parathyroid hormone Irritability Gastroenterology lcsh:Gynecology and obstetrics vitamin D deficiency 03 medical and health sciences Young Adult 0302 clinical medicine Dysmenorrhea Internal medicine medicine Vitamin D and neurology Humans 030212 general & internal medicine Prospective Studies Vitamin D Prospective cohort study lcsh:RG1-991 Hyperparathyroidism 030219 obstetrics & reproductive medicine business.industry Obstetrics and Gynecology medicine.disease Vitamin D Deficiency Dairy product Cohort Female medicine.symptom business |
| Zdroj: | Taiwanese Journal of Obstetrics & Gynecology, Vol 57, Iss 1, Pp 58-63 (2018) |
| ISSN: | 1028-4559 |
| Popis: | Objective: This study aims to investigate the possible role of vitamin D deficiency in primary dysmenorrhea by assessing serum 25-hydroxyvitamin D3 levels in a cohort which includes young Turkish women with primary dysmenorrhea and healthy controls. Materials and methods: A total of 683 women who were aged between 18 and 25 years and who were consecutively admitted to the study center were eligible. After the exclusion of 55 women, 184 women with primary dysmenorrhea were randomly assigned into the dysmenorrhea group and 184 women without dysmenorrhea were randomly allocated into the control group. Results: The dysmenorrhea group had significantly less consumption of dairy products (p = 0.001), lower serum calcium (p = 0.001), lower serum vitamin D (p = 0.001) and higher serum parathyroid hormone (p = 0.001) than those of the control group. Hyperparathyroidism was significantly less frequent whereas vitamin D deficiency was significantly more frequent in the dysmenorrhea group (p = 0.001 for each). The dysmenorrhea patients with vitamin D deficiency had significantly higher visual analogue scale (VAS) scores (p = 0.001). Depression, irritability, mood swings, fatigue, headache and breast tenderness were significantly more frequent in the vitamin D deficiency group (p |
| Databáze: | OpenAIRE |
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