Moderate intensity exercise training reverses functional aerobic impairment in HIV-infected individuals

Autor: Wesley D. Dudgeon, J. Larry Durstine, Stephanie Burgess, Gregory A. Hand, Kenneth D. Phillips, G. William Lyerly
Rok vydání: 2008
Předmět:
Zdroj: AIDS Care. 20:1066-1074
ISSN: 1360-0451
0954-0121
DOI: 10.1080/09540120701796900
Popis: HIV infection and HIV drug therapies result in physical and psychological challenges to those living with HIV. These conditions contribute to decreased functional aerobic capacity (FAC). The aim of this study was to determine the effects of a combined moderate-intensity aerobic and resistance exercise intervention on the FAC of HIV-infected individuals. Forty HIV-infected individuals were randomized to an exercise group (EX) who completed six weeks of moderate-intensity exercise training, or to a control group (CON) that did not receive the exercise intervention. Twice weekly, the EX group completed 30 minutes of moderate-intensity aerobic training followed by moderate-intensity resistance training. Prior to, and following, the intervention the FAC for each subject was determined by graded exercise treadmill stress test (GXT). At baseline testing, the mean FAC as determined by treadmill time-based estimation of maximal oxygen consumption was 25% below age-predicted values, a level of reduction indicating the presence of functional aerobic impairment (FAI). Following the intervention, the EX had a significant increase in time to fatigue and estimated VO(2) max (p
Databáze: OpenAIRE
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