Antihyperlipidemic effect of chlorogenic acid and tetrahydrocurcumin in rats subjected to diabetogenic agents

Autor:	Krishnamoorthy Karthikesan, Leelavinothan Pari, Venugopal P. Menon
Rok vydání:	2010
Předmět:	Male Niacinamide Very low-density lipoprotein medicine.medical_specialty Curcumin Lipoproteins Blood lipids Toxicology Diabetes Mellitus Experimental Phosphatidylcholine-Sterol O-Acyltransferase chemistry.chemical_compound High-density lipoprotein Internal medicine medicine Animals Rats Wistar Hypolipidemic Agents Lipoprotein lipase Cholesterol nutritional and metabolic diseases Lipid metabolism General Medicine Streptozotocin Rats Drug Combinations Lipoprotein Lipase Endocrinology Liver chemistry Low-density lipoprotein Hydroxymethylglutaryl CoA Reductases lipids (amino acids peptides and proteins) Chlorogenic Acid medicine.drug
Zdroj:	Chemico-Biological Interactions. 188:643-650
ISSN:	0009-2797
DOI:	10.1016/j.cbi.2010.07.026
Popis:	Diabetes mellitus is associated with dyslipidemia, which is a significant risk factor for cardiovascular complications. The present study was carried out to evaluate the effects of tetrahydrocurcumin (THC) and chlorogenic acid (CGA) alone and in combination on alterations in lipids, lipoproteins and enzymes involved in lipid metabolism in streptozotocin (STZ)-nicotinamide (NA)-induced type 2 diabetic rats. A significant (p
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a32fce4dd3e33aa1f87c072086b0c704 https://doi.org/10.1016/j.cbi.2010.07.026 Zobrazit plný text záznamu Full Text from ScienceDirect