Hormonal and Inflammatory Responses to Hypertrophy-Oriented Resistance Training at Acute Moderate Altitude
| Autor: | Josefa León, Sergio Pérez-Regalado, Brad J. Schoenfeld, Juan Bonitch-Góngora, Paulino Padial, Belén Feriche, Cristina Benavente, Filipa Almeida |
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| Přispěvatelé: | [Benavente,C, Feriche,B, Bonitch-Góngora,J, Almeida,F, Pérez-Regalado,S, Padial,P] Department of Physical Education and Sport, Faculty of Sport Sciences, University of Granada, Granada, Spain. [León,J] Clinical Management Unit of Digestive System, San Cecilio Hospital, ibs.GRANADA, Granada, Spain. [Schoenfeld,BJ] Department of Health Sciences, CUNY Lehman College, Bronx, NY, USA., This research was funded by the Spanish Ministry of Science, Innovation and Universities, grant number PGC2018-097388-B-I00, by the Andalusian FEDER Operational Program, grant number A-SEJ-246-UGR18 and FPU pre-doctoral, grant number FPU18/00686 awarded to one of the authors. |
| Rok vydání: | 2021 |
| Předmět: |
Male
Hydrocortisone Health Toxicology and Mutagenesis Phenomena and Processes::Biological Phenomena::Ecological and Environmental Phenomena::Environment::Altitude [Medical Subject Headings] Muscle hypertrophy Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Primates::Haplorhini::Catarrhini::Hominidae::Humans [Medical Subject Headings] Basal (phylogenetics) 0302 clinical medicine Persons::Persons::Men::Nurses Male [Medical Subject Headings] Testosterone Hipoxia Analytical Diagnostic and Therapeutic Techniques and Equipment::Therapeutics::Physical Therapy Modalities::Exercise Therapy::Resistance Training [Medical Subject Headings] Hypoxia MicroARNs 0303 health sciences Human Growth Hormone Altitude Citocinas Anatomy::Musculoskeletal System::Muscles::Muscle Skeletal [Medical Subject Headings] Venous blood Interleukin 10 Cytokines Medicine Tumor necrosis factor alpha Strength medicine.symptom strength medicine.medical_specialty Terrestrial altitude Article 03 medical and health sciences Internal medicine Chemicals and Drugs::Amino Acids Peptides and Proteins::Peptides::Peptide Hormones::Pituitary Hormones::Pituitary Hormones Anterior::Growth Hormone::Human Growth Hormone [Medical Subject Headings] medicine Humans Muscle Skeletal Chemicals and Drugs::Polycyclic Compounds::Steroids::Pregnanes::Pregnenes::Pregnenediones::Hydrocortisone [Medical Subject Headings] miRNA 030304 developmental biology hypoxia business.industry Public Health Environmental and Occupational Health Resistance Training Hypertrophy 030229 sport sciences Hypoxia (medical) cytokines Entrenamiento de fuerza Endocrinology terrestrial altitude Chemicals and Drugs::Polycyclic Compounds::Steroids::Androstanes::Androstenes::Androstenols::Testosterone::Testosterone Propionate [Medical Subject Headings] business Hormone |
| Zdroj: | International Journal of Environmental Research and Public Health, Vol 18, Iss 4233, p 4233 (2021) Digibug. Repositorio Institucional de la Universidad de Granada instname International Journal of Environmental Research and Public Health Volume 18 Issue 8 Digibug: Repositorio Institucional de la Universidad de Granada Universidad de Granada (UGR) |
| ISSN: | 1660-4601 |
| DOI: | 10.3390/ijerph18084233 |
| Popis: | This study investigated the effect of a traditional hypertrophy-oriented resistance training (RT) session at acute terrestrial hypoxia on inflammatory, hormonal, and the expression of miR-378 responses associated with muscular gains. In a counterbalanced fashion, 13 resistance trained males completed a hypertrophic RT session at both moderate-altitude (H 2320 m asl) and under normoxic conditions (N < 700 m asl). Venous blood samples were taken before and throughout the 30 min post-exercise period for determination of cytokines (IL6, IL10, TNFα), hormones (growth hormone [GH], cortisol [C], testosterone), and miR-378. Both exercise conditions stimulated GH and C release, while miR-378, testosterone, and inflammatory responses remained near basal conditions. At H, the RT session produced a moderate to large but nonsignificant increase in the absolute peak values of the studied cytokines. miR-378 revealed a moderate association with GH (r = 0.65 p = 0.026 and r = −0.59 p = 0.051 in N and H, respectively) and C (r = 0.61 p = 0.035 and r = 0.75 p = 0.005 in N and H, respectively). The results suggest that a RT session at H does not differentially affect the hormonal, inflammatory, and miR-378 responses compared to N. However, the standardized mean difference detected values in the cytokines suggest an intensification of the inflammatory response in H that should be further investigated. |
| Databáze: | OpenAIRE |
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