3D visualization of the regional differences

Autor: David R. Hampson, Toru Takumi, Christopher L. Muller, Elaine Tam, M. C. van Eede, Daniel H. Geschwind, Nobuhiro Nakai, Alea A. Mills, Zhong Xuan, F. Espinosa-Becerra, Jeremy Veenstra-VanderWeele, Lucy R. Osborne, R. M. Henkelman, Jacqueline N. Crawley, Emanuel DiCicco-Bloom, Laura K. K. Pacey, Travis M. Kerr, Jin Nakatani, Jason P. Lerch, Olga Peñagarikano, Jonathan Lai, Craig M. Powell, Jane A. Foster, Brooke A. Babineau, Diane M. Robins, C. L. Laliberté, Evdokia Anagnostou, Lulu Lin, Jacob Ellegood, Matthieu Genestine, Mehreen Kouser, Randy D. Blakely, Armin Raznahan
Rok vydání: 2015
Předmět:
Zdroj: Molecular Psychiatry. 20:1-1
ISSN: 1476-5578
1359-4184
DOI: 10.1038/mp.2014.168
Popis: We examined 26 different mouse models related to autism and identified three groups that shared similar neuroanatomical phenotypes. These three groups and their regional differences are shown here. Anything highlighted in red was determined to be larger in that group (median effect size for group >0.5) and anything highlighted in blue was determined to be smaller in that group (median effect size for group < − 0.5). These differences are shown in 3D in an axial representation either looking from above (a) or below (b) the mouse brain. For more information on this topic, please refer to the article by Ellegood et al on pages 118–125.
Databáze: OpenAIRE