Towards Optical Biopsies with an Integrated Fibered Confocal Fluorescence Microscope
| Autor: | Benjamin Abrat, Georges Le Goualher, Aymeric Perchant, Magalie Genet, Frederic Berier, Nicholas Ayache, Charlotte Cave, Bertrand Viellerobe |
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| Přispěvatelé: | Mauna Kea Technologies, Medical imaging and robotics (EPIDAURE), Inria Sophia Antipolis - Méditerranée (CRISAM), Institut National de Recherche en Informatique et en Automatique (Inria)-Institut National de Recherche en Informatique et en Automatique (Inria), Barillot, Christian and Haynor, David and Hellier, Pierre |
| Jazyk: | angličtina |
| Rok vydání: | 2004 |
| Předmět: |
Image formation
Materials science Channel (digital image) Endoscope business.industry [SDV.IB.IMA]Life Sciences [q-bio]/Bioengineering/Imaging Confocal Image processing software Optical Biopsy [INFO.INFO-MO]Computer Science [cs]/Modeling and Simulation [INFO.INFO-TS]Computer Science [cs]/Signal and Image Processing Medical imaging Fluorescence microscope [INFO.INFO-IM]Computer Science [cs]/Medical Imaging Computer vision Artificial intelligence business [SPI.SIGNAL]Engineering Sciences [physics]/Signal and Image processing ComputingMilieux_MISCELLANEOUS Biomedical engineering |
| Zdroj: | Proc. of MICCAI'04 Proc. of MICCAI'04, 2004, Saint-Malo, France, France. pp.761--768 Medical Image Computing and Computer-Assisted Intervention – MICCAI 2004 ISBN: 9783540229773 MICCAI (2) |
| Popis: | This paper presents an integrated endoscope-compatible Fibered Confocal Fluorescence Microscope (FCFM) for medical imaging, the F-400. In situ high resolution images can be obtained thanks to a set of flexible miniaturized optical probes of 0.5 to 1.5 mm diameter that can be inserted through the working channel of an endoscope. We briefly present in this paper the FCFM system, with a particular focus on the image formation and the design of a dedicated image processing software allowing for drastically reduce the inherent artifacts occurring when imaging through an image bundle. The goal of the FCFM is to perform optical biopsy (i.e. in vivo and in situ observations of thin sections of biological tissues at the cellular level). As a first step towards this goal, we present here results of a clinical trial assessing the ability of the F-400 to perform rapid morphologic examination in the endoscopy room of medical specimens (polypectomy). |
| Databáze: | OpenAIRE |
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