A new class of metal-free catalysts for direct diastereo- and regioselective Mannich reactions in aqueous media

Autor:	Jiwen Cai, Guang-Xin Lin, Zhi-Ya Hu, Yin-Su Wu
Rok vydání:	2004
Předmět:	chemistry.chemical_classification Aqueous medium Organic Chemistry Regioselectivity General Medicine Sulfonic acid Biochemistry Amino acid Benzaldehyde Metal free catalysts Camphor chemistry.chemical_compound Aniline chemistry Drug Discovery Organic chemistry
Zdroj:	Tetrahedron Letters. 45:8949-8952
ISSN:	0040-4039
DOI:	10.1016/j.tetlet.2004.09.174
Popis:	Camphor sulfonic acid is an efficient catalyst for Mannich reactions of benzaldehyde, aniline and various ketones in aqueous media, with diastereo- or regioselectivities. Meanwhile, three sulfonated amino acids can catalyze the same type of reactions effectively with high diastereo- or regioselectivities.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a312785083737023109a23c6f4d6f27b https://doi.org/10.1016/j.tetlet.2004.09.174 Zobrazit plný text záznamu Full Text from ScienceDirect