Startle responses after different stimulus modalities differ in stroke
| Autor: | Melis Sohtaoğlu, Melda Bozluolcay, Aysegul Gunduz, Meral E. Kiziltan |
|---|---|
| Rok vydání: | 2015 |
| Předmět: |
0301 basic medicine
Male medicine.medical_specialty Reflex Startle genetic structures Stimulus (physiology) Audiology Reticular formation Somatosensory system Biceps 03 medical and health sciences 0302 clinical medicine Auditory startle Physiology (medical) Physical Stimulation Moro reflex medicine Humans Prospective Studies Muscle Skeletal Stroke Electromyography General Medicine Middle Aged medicine.disease SSS 030104 developmental biology Neurology Acoustic Stimulation Female sense organs Neurology (clinical) Psychology Neuroscience 030217 neurology & neurosurgery |
| Zdroj: | Neurophysiologie clinique = Clinical neurophysiology. 46(3) |
| ISSN: | 1769-7131 |
| Popis: | Summary Objectives The auditory startle reaction (ASR) and startle reflex to somatosensory inputs (SSS) are stereotypical responses to sudden and unexpected stimuli, which are generated in the caudal brainstem reticular formation. Changes of ASR are relatively well known in stroke. Here, we aimed to investigate central pathways of SSS and plasticity changes of SSS circuits in different stages and localizations of stroke, by comparing with ASR. Methods We prospectively included 39 patients with stroke between June 2009 and June 2013, and 23 age and gender-matched healthy subjects. ASR and SSS were recorded over orbicularis oculi, sternocleidomastoid, biceps brachii (BB), and abductor policis brevis muscles (APB) using surface electrodes. Results There were supratentorial and infratentorial lesions in both acute and chronic stages. Overall, ASR probability was similar between groups (P = 0.981). However, ASR probability was increased for BB and APB recordings on symptomatic sides of stroke patients with high amplitudes and long durations, most prominently on symptomatic sides of pontine strokes. Latencies and presence rates of SSS did not differ between any subgroups of stroke and healthy subjects. Conclusion ASR is facilitated in arm and hand muscles on symptomatic sides of stroke patients, whereas SSS did not show any significant changes according to stroke. |
| Databáze: | OpenAIRE |
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