Estrogen Receptors in Colorectal Adenocarcinomas and in Other Large Bowel Diseases
| Autor: | Enrichens F, Olivero G, Comandone A, Sciascia C, Fiori Mg, Festa T |
|---|---|
| Rok vydání: | 1990 |
| Předmět: |
Male
Cancer Research Colon Clinical Biochemistry Estrogen receptor 030209 endocrinology & metabolism Disease Adenocarcinoma Pathology and Forensic Medicine Immunoenzyme Techniques Colonic Diseases 03 medical and health sciences 0302 clinical medicine Tumor stage Humans Medicine Protamines Aged business.industry Dextrans Middle Aged Cytosol Receptors Estrogen Oncology Cytosolic receptor 030220 oncology & carcinogenesis Recurrent Cancer Cancer research Female Colorectal Neoplasms business |
| Zdroj: | Scopus-Elsevier |
| ISSN: | 1724-6008 |
| DOI: | 10.1177/172460089000500108 |
| Popis: | Seventy-two patients with tumor and ten with non-neoplastic colon disease were studied for the presence of estrogen receptors (ER) by three different methods. Only seven specimens (six primary adenocarcinomas and one recurrent cancer) had an ER concentration above 3 fm/mg of cytosolic protein, with no sex, age and tumor stage correlation. Our results suggest that the large bowel does not contain a cytosolic receptor for estradiol. |
| Databáze: | OpenAIRE |
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