Specific immunological unresponsiveness following active primary responses to proteins in the weaning diet of piglets
| Autor: | E. Telemo, Mick Bailey, F.J. Bourne, B. G. Miller, Christopher R. Stokes |
|---|---|
| Rok vydání: | 1993 |
| Předmět: |
Male
medicine.medical_specialty Time Factors Ovalbumin Swine animal diseases medicine.medical_treatment Immunology Systemic injection Administration Oral Weaning Biology Plant Proteins Dietary Antibodies Immune tolerance fluids and secretions Immune system Oral administration Internal medicine medicine Immune Tolerance Immunology and Allergy Animals Plant Proteins food and beverages General Medicine Animal Feed Endocrinology Humoral immunity Antibody Formation biology.protein Soybean Proteins Weaning diet Female Dietary Proteins Soybeans Antibody Adjuvant Food Hypersensitivity Injections Intraperitoneal |
| Zdroj: | International archives of allergy and immunology. 101(3) |
| ISSN: | 1018-2438 |
| Popis: | Young piglets weaned onto soya diets frequently develop diarrhoea which may have a dietary and/or immunological component. Piglets abruptly weaned onto soya at 3 weeks of age developed levels of serum IgG anti-soya antibodies almost comparable to those induced by injection with soya protein in adjuvant at 7 weeks. In the piglets primed by feeding, no significant further increase in antibody occurred after subsequent systemic injection. In contrast, secondary responses were observed in age-matched animals, previously primed by injection, and primary responses were obtained in previously naive piglets. The results demonstrate the development of specific unresponsiveness to soya proteins in neonates fed soya, despite the occurrence of an initial vigorous immune response to the fed protein. |
| Databáze: | OpenAIRE |
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