The effect of Cordia platythyrsa on various experimental models of pain and carrageenan induced inflammation
| Autor: | Joseph T Mbafor, Lonwabo A. Dotwana, Benedicta N. Nkeh-Chungag, E. J. Ndebia, Opeopluwa Oyehan Oyedeji, Jehu E Iputo |
|---|---|
| Rok vydání: | 2014 |
| Předmět: |
Aspirin
biology business.industry Carrageenan induced inflammation Analgesic Inflammation Pharmacology Cordia platythyrsa biology.organism_classification Applied Microbiology and Biotechnology Genetics Morphine Celecoxib Medicine African traditional medicine medicine.symptom business Agronomy and Crop Science Molecular Biology Biotechnology medicine.drug |
| Zdroj: | African Journal of Biotechnology; Vol 13, No 2 (2014) |
| ISSN: | 1684-5315 |
| Popis: | Only one study has reported on the medicinal properties of Cordia platythyrsa (C. platythyrsa) though it is used in African traditional medicine for treatment of fever and pain. The current study aimed at investigating the analgesic and anti-inflammatory properties of C. platythyrsa using various animal models: writhing test, tail flick, thermal hyperalgesia, mechanically induced-pain, formalin-induced pain and carrageenan-induced inflammation tests. Like aspirin, the two doses of plant extracts used inhibited acetic acid-induced pain though these effects were weaker than the effects of morphine. Although, the plant extract significantly (p |
| Databáze: | OpenAIRE |
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