A rating scale for the assessment of objective and subjective formal thought and language disorder (TALD)
| Autor: | Axel Krug, Tilo Kircher, Michael Grosvald, Mirjam Stratmann, Christian Schales, Paul Fährmann, Rüdiger Müller-Isberner, Tobias Hornig, Arne Nagels, Michael Katzev, Lena Turner, Sayed Ghazi, Michael Frauenheim |
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| Jazyk: | angličtina |
| Rok vydání: | 2014 |
| Předmět: |
Adult
Male medicine.medical_specialty Bipolar Disorder Psychometrics Principal component analyses Thinking Correlation Formal thought disorder Rating scale Interview Psychological Healthy control Hamd mental disorders medicine Humans Language disorder Medical diagnosis Psychiatry Biological Psychiatry Language Psychiatric Status Rating Scales Depressive Disorder Principal Component Analysis Depression Thought disorder Middle Aged medicine.disease Psychiatry and Mental health Mania Schizophrenia Female medicine.symptom Factor Analysis Statistical Psychology |
| Popis: | Formal thought disorder (FTD) is a core syndrome of schizophrenia. However, patients with other diagnoses, such as mania and depression amongst others, also present with FTD. We introduce a novel, comprehensive clinical rating scale, capturing the full variety of FTD phenomenology including subjective experiences. The 30-item Thought and Language Disorder (TALD) scale is based on a detailed review of the literature, encompassing all formal thought disorder symptoms reported from the early 20th century onwards. Objectively observable symptoms as well as subjective phenomena were included. Two hundred and ten participants (146 patients ICD-10 diagnoses: depression n. = 63, schizophrenia n. = 63, mania n. = 20; 64 healthy control subjects) were interviewed and symptoms rated with the TALD, TLC, HAMD, YMRS and SAPS/SANS. A principal component analyses was performed for the TALD to differentiate sub-syndromes. The principal component analysis revealed four FTD factors; objective and subjective as well as positive and negative factor dimensions. The correlation analyses with the TLC and the SAPS/SANS FTD sub-scores demonstrated the factor validity for the objective factors. The different diagnoses showed a distinct pattern of symptom severity in each of the factors, with mania patients exhibiting the highest value in the positive, objective dimension. The scale showed good psychometric results, which makes it a practicable, nosologically-open instrument for the detailed assessment of all FTD dimensions. The results strengthen the importance of subjective symptom assessment reported by the patient. DFG (project no. Ki 588/6-1) Scopus |
| Databáze: | OpenAIRE |
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