Presence of repeater F-waves in the early stage of Guillain-Barré syndrome

Autor: Emilio Geijo-Barrientos, Ofelia González, Carlos Pastore-Olmedo
Rok vydání: 2012
Předmět:
Zdroj: Digital.CSIC. Repositorio Institucional del CSIC
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ISSN: 1085-9489
DOI: 10.1111/j.1529-8027.2012.00383.x
Popis: The absence or a prolonged latency of late responses, like F-waves, is a common neurophysiological finding with diagnostic utility in the early Guillain-Barrésyndrome. However, the presence and the number of repeater F-waves have not been studied in this disease. In four patients, we report the transient presence of repeater F-waves in nerves of the lower limbs shortly after the onset of the disease. In each patient, the initial (diagnostic) nerve conduction study showed a high incidence of repeater F-waves in the tibial or in the peroneal nerves of one side, with normal distal motor latencies; in the other nerves explored the F-waves were fully abolished and the motor potentials were abnormal. In a second study, done 2-6 weeks later, we observed the abolition of the F-waves or a significant increase of its minimal latency in those nerves in which we had detected the repeaters. The presence of a high number of repeater F-waves with normal latencies in some nerves may be a transient and initial electrophysiological sign useful in the early diagnosis of this disease. © 2012 Peripheral Nerve Society.
Work supported by Fundación Gent per Gent, Prometeo program CIBERSAM and Consolider-Ingenio programme CSD2007-0023.
Databáze: OpenAIRE