Combined use of isotopic fingerprint and metabolomics analysis for the authentication of saw palmetto (Serenoa repens) extracts
| Autor: | Giovanni Appendino, Francesca Vitulo, Ernesto Marco Martinelli, Matteo Perini, Federica Camin, Eric de Combarieu, Nicola Sardone, Mauro Paolini, Roberto Pace |
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| Rok vydání: | 2018 |
| Předmět: |
Stable isotope analysis
Combined use Economic shortage Biology 01 natural sciences Animal origin Metabolomics Serenoa Saw palmetto Drug Discovery Plant Oils Serenoa repens Food science Settore CHIM/10 - CHIMICA DEGLI ALIMENTI Pharmacology Principal Component Analysis Plant Extracts 010405 organic chemistry Fatty Acids 010401 analytical chemistry General Medicine Lipids NMR 0104 chemical sciences Adulteration Drug Contamination |
| Zdroj: | Fitoterapia. 127:15-19 |
| ISSN: | 0367-326X |
| Popis: | Saw palmetto (Serenoa repens, SP) is the most expensive oil source of the pharmaceutical and healthfood market, and its high cost and recurrent shortages have spurred the development of designer blends of fatty acids to mimic its phytochemical profile and fraudulently comply with the current authentication assays. To detect this adulteration, the combined use of isotopic fingerprint and omic analysis has been investigated, using Principal Component Analysis (PCA) to handle the complex databases generated by these techniques and to identify the possible source of the adulterants. Surprisingly, the presence of fatty acids of animal origin turned out to be widespread in commercial samples of saw palmetto oil. |
| Databáze: | OpenAIRE |
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