Synthesis, Antibacterial and Antifungal Activity of 4-Substituted-5-Aryl-1,2,4-Triazoles
| Autor: | Vesna Dimova, Dora Gabor Molnar, Vlado Kakurinov, Katica Colanceska-Ragenovic, Aleksandra Buzarovska |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2001 |
| Předmět: |
cyclization
Salmonella enteritidis Hydrazine Pharmaceutical Science Bacillus subtilis 1 2 4-triazoles medicine.disease_cause Article Substituted benzoyl/phenylcetyl-4-allylthiosemicarbazides 1 2 4-triazoles inhibition zone Analytical Chemistry lcsh:QD241-441 chemistry.chemical_compound lcsh:Organic chemistry Drug Discovery medicine Organic chemistry Physical and Theoretical Chemistry Candida albicans Escherichia coli biology Aryl Organic Chemistry Aspergillus niger biology.organism_classification chemistry Chemistry (miscellaneous) Staphylococcus aureus Molecular Medicine |
| Zdroj: | Molecules, Vol 6, Iss 10, Pp 815-824 (2001) Scopus-Elsevier Molecules; Volume 6; Issue 10; Pages: 815-824 Molecules : A Journal of Synthetic Chemistry and Natural Product Chemistry |
| ISSN: | 1420-3049 |
| Popis: | A few 4-allyl/amino-5-aryl-1,2,4-triazoles were synthesized and tested for antibacterial and antifungal effects against Escherichia coli, Bacillus subtilis, Salmonella enteritidis, Staphylococcus aureus, Aspergillus niger and Candida albicans. 4-Allyl-5-aryl-1,2,4-triazoles were obtained by the oxidative cyclization of the appropriate 1-substituted-4-allylthiosemicarbazides and 4-amino-5-aryl-1,2,4-triazoles were obtained by cyclization of the potassium salts of appropriately substituted dithiocarbazinic acids with hydrazine hydrate. The new synthesized compounds were characterized using IR, 1H- NMR, 13C-NMR and UV spectral data together with elemental analysis. |
| Databáze: | OpenAIRE |
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