Baseline Health-Related Quality of Life and 10-Year All-Cause Mortality among 1739 Chinese Adults
| Autor: | Fuxiu Ren, Joseph R. Egger, Wei Gao, Daniel T. Laskowitz, Elizabeth L. Turner, Yangfeng Wu, Ping Shi, Gaoqiang Xie |
|---|---|
| Rok vydání: | 2014 |
| Předmět: |
Adult
Male Gerontology China medicine.medical_specialty Epidemiology Population lcsh:Medicine Global Health Quality of life Risk Factors Internal medicine Mental Health and Psychiatry Medicine and Health Sciences medicine Humans Public and Occupational Health Prospective Studies Mortality lcsh:Science Prospective cohort study education Aged Proportional Hazards Models education.field_of_study Multidisciplinary business.industry Proportional hazards model Mortality rate lcsh:R Hazard ratio Middle Aged Confidence interval 3. Good health Population Surveillance Quality of Life Marital status Female lcsh:Q business Research Article |
| Zdroj: | PLoS ONE, Vol 9, Iss 7, p e101527 (2014) PLoS ONE |
| ISSN: | 1932-6203 |
| DOI: | 10.1371/journal.pone.0101527 |
| Popis: | Background and Purpose Health-related quality of life (HRQOL) may be associated with the longevity of patients; yet it is not clear whether this association holds in a general population, especially in low- and middle-income countries. The objective of this study was to determine whether baseline HRQOL was associated with 10-year all-cause mortality in a Chinese general population. Methods A prospective cohort study was conducted from 2002 to 2012 on 1739 participants in 11 villages of Beijing. Baseline data on six domains of HRQOL, chronic diseases and cardiovascular risk factors were collected in either 2002 (n = 1290) or 2005 (n = 449). Subjects were followed through the end of the study period, or until they were censored due to death or loss to follow-up, whichever came first. Results A multivariable Cox model estimated that Total HRQOL score (bottom 50% versus top 50%) was associated with a 44% increase in all-cause mortality (Hazard Ratio [HR] = 1.44; 95% confidence interval [CI]: 1.00-2.06), after adjusting for sex, age, education levels, occupation, marital status, smoking status, fruit intake, vegetable intake, physical exercise, hypertension, history of a stroke, myocardial infarction, chronic respiratory disease, and kidney disease. Among the six HRQOL domains, the Independence domain had the largest fully adjusted HR (HR = 1.66; 95% CI: 1.13-2.42), followed by Psychological (HR = 1.47; 95% CI: 1.03-2.09), Environmental (HR = 1.43, 95% CI: 1.003-2.03), Physical (HR = 1.38; 95% CI: 0.97-1.95), General (HR = 1.37; 95% CI: 0.97-1.94), and the Social domain (HR = 1.15; 95% CI: 0.81-1.65). Conclusion Lower HRQOL, especially the inability to live independently, was associated with a significantly increased risk of 10-year all-cause mortality. The inclusion of HRQOL measures in clinical assessment may improve diagnostic accuracy to improve clinical outcomes and better target public health promotions. |
| Databáze: | OpenAIRE |
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