Clinical Characteristics and Outcome of Pneumomediastinum in Patients with COVID-19 Pneumonia
Autor: | Arony Sun, Ory Wiesel, Aaron Kangas-Dick, Mudathir Ibrahim, Jason P. Shaw, Igor Brichkov, Victor Gazivoda |
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Jazyk: | angličtina |
Rok vydání: | 2021 |
Předmět: |
Male
medicine.medical_specialty Pediatrics 03 medical and health sciences 0302 clinical medicine medicine Humans Pneumomediastinum Pandemics Mediastinal Emphysema Aged Retrospective Studies Respiratory distress SARS-CoV-2 business.industry Incidence (epidemiology) COVID-19 Mediastinum Middle Aged Prognosis medicine.disease Surgery Pneumonia medicine.anatomical_structure Pneumothorax 030220 oncology & carcinogenesis Etiology Female 030211 gastroenterology & hepatology business Airway |
Zdroj: | Journal of Laparoendoscopic & Advanced Surgical Techniques |
ISSN: | 1557-9034 1092-6429 |
DOI: | 10.1089/lap.2020.0692 |
Popis: | Introduction: Pneumomediastinum (PM) is characterized by the presence of air within the mediastinum. The association between PM and coronavirus 2019 (COVID-19) has not been well established in the current literature. We sought to summarize the limited body of literature regarding PM in patients with COVID-19 and characterize the presentation and clinical outcomes of PM in patients with severe acute respiratory syndrome (SARS)-COV-2 pneumonia at our institution to better define the incidence, prognosis, and available treatment for this condition. Materials and Methods: All patients with a proven diagnosis of COVID-19 and PM between March 18, 2020 and May 5, 2020 were identified through hospital records. Retrospective analysis of radiology records and chart review were conducted. Clinical characteristics and outcomes were collected and descriptive statistics was analyzed. Results: Thirty-six patients met inclusion criteria. Out of the 346 intubated COVID-19 patients, 34 (10%) had PM. The incidence of PM increased for the first 4 weeks of the pandemic, and then began to decrease by week 5. At the endpoint of the study, 12 (33.33%) patients were alive and 24 patients (66.67%) had died. Conclusion: PM, although a rare phenomenon, was more prevalent in COVID-19 patients compared with historical patients with adult respiratory distress syndrome. The etiology of this condition may be attributed to higher susceptibility of patients infected with SARS-CoV-2 to a combination of barotrauma and airway injury. |
Databáze: | OpenAIRE |
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