Prevalence of the five newborn screening tests

Autor: Jéssica Rodrigues Clementino, Josilene Maria Ferreira Pinheiro, Luana Isabelly Carneiro de Oliveira, Cristiane da Silva Ramos Marinho, Vanessa Cristina da Costa Pires, Fábia Barbosa de Andrade, Mara Rúbia de Oliveira Bezerra, Taiana Brito Menêzes Flor
Rok vydání: 2021
Předmět:
Health Screening
Maternal Health
Social Sciences
Neonatal Care
Pediatrics
Geographical locations
Sociology
Pregnancy
Reflexes
Medicine and Health Sciences
Public and Occupational Health
Human Families
Virus Testing
Multidisciplinary
medicine.diagnostic_test
Obstetrics
Hearing Tests
Mortality rate
Test (assessment)
medicine.anatomical_structure
symbols
Medicine
Female
Anatomy
Brazil
Research Article
medicine.medical_specialty
Science
Hospitals
Maternity

Hospitals
Private

symbols.namesake
Neonatal Screening
Red reflex
Tongue
Diagnostic Medicine
medicine
Humans
Poisson regression
Mouth
Newborn screening
Hospitals
Public

business.industry
Infant
Newborn

Biology and Life Sciences
Neonates
South America
Confidence interval
Health Care
Pulse oximetry
Cross-Sectional Studies
Women's Health
Neonatology
People and places
business
Digestive System
Developmental Biology
Neuroscience
Zdroj: PLoS ONE, Vol 16, Iss 9, p e0257282 (2021)
PLoS ONE
ISSN: 1932-6203
DOI: 10.1371/journal.pone.0257282
Popis: Neonatal screening is essential for child health and has the following purposes: (1) pulse oximetry screening to evaluate congenital heart diseases; (2) red reflex examination to investigate eye diseases; (3) newborn hearing screening test to evaluate congenital hearing diseases; (4) tongue test to evaluate the lingual frenulum and identify communication and feeding problems; (5) the Guthrie test to screen for metabolic diseases. This study investigated the prevalence of the five neonatal screening tests and its associated institutional and socio-cultural factors using a cross-sectional study with 415 mother and baby binomials from public maternity hospitals in Natal, RN, Brazil in 2019. Pearson’s chi-squared, Mann-Whitney and Poisson regression tests were used, with a significance of p ≤ 0.05 and a 95% confidence interval. The sample loss was 71 mothers (17%). The prevalence in the first week and at the end of 28 days was 93% and 99.5% (pulse oximetry screening), 60% and 97.6% (red reflex examination), 71.9% and 93.6% (Guthrie test), 35.5% and 68.2% (hearing screening test), and 19% and 48.9% (tongue test). Only 152 newborns (36.6%) underwent all five tests. The performance of the tests was associated in the final model (p ≤ 0.05) with the residence of the mothers in the state capital (PR = 1.36; 95% CI = 1.18–1.56) and the provision of guidance for mothers about the five tests in maternity hospitals (PR = 1.30; 95% CI = 1.08–1.67). None of the tests met full coverage, and regional inequities were identified indicating the need to restructure the institutions, training and qualification procedures to improve of the work processes and longitudinal care.
Databáze: OpenAIRE