Evaluation of predictor variables of diagnostic [18F] FDG-PET/CT in fever of unknown origin

Autor: Ozgur Karacalioglu, Engin Alagoz, Kursat Okuyucu, Ahmet Karakaş, Seref Demirbas, Semra Ince, Bengul Gunalp, Nuri Arslan
Rok vydání: 2018
Předmět:
Zdroj: The Quarterly Journal of Nuclear Medicine and Molecular Imaging. 62
ISSN: 1827-1936
1824-4785
DOI: 10.23736/s1824-4785.17.02833-3
Popis: BACKGROUND Fever of unknown origin (FUO) is defined as an illness having fever which lasts at least 3 weeks of duration and is higher than 38.3 oC on several measurements. The causes are infections, malignancies, noninfectious inflammatory diseases and miscellaneous. If [18F]FDG-PET/CT helps the final diagnosis, it is called contributory. The aim of the study is to evaluate the predictor variables effecting a contributory PET/CT for the diagnosis. METHODS This is a retrospective cohort study conducted between June 2006 and May 2015 including 76 patients. The evaluated predictor variables are age, sex, ESR, CRP, fibrinogen, ferritin, albumin, haemoglobin level, platelet count, total leukocyte count, neutrophil percentage, lymphocyte percentage, ALP, LDH, ALAT, ASAT, GGT, total bilirubin, CK, RF, ANA, urinanalysis, chest radiography, abdominal US, lymphadenopathy, duration of fever, comorbid diseases and previous therapies. RESULTS ESR (P=0.001), CRP (P=0.001), fibrinogen (P=0.009), lymphopenia (P
Databáze: OpenAIRE