Evaluation of predictor variables of diagnostic [18F] FDG-PET/CT in fever of unknown origin
| Autor: | Ozgur Karacalioglu, Engin Alagoz, Kursat Okuyucu, Ahmet Karakaş, Seref Demirbas, Semra Ince, Bengul Gunalp, Nuri Arslan |
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| Rok vydání: | 2018 |
| Předmět: |
Adult
Male medicine.medical_specialty Pathology Adolescent Bilirubin Fibrinogen Fever of Unknown Origin Gastroenterology 030218 nuclear medicine & medical imaging Young Adult 03 medical and health sciences chemistry.chemical_compound 0302 clinical medicine Fluorodeoxyglucose F18 Positron Emission Tomography Computed Tomography Internal medicine medicine Humans Radiology Nuclear Medicine and imaging Leukocytosis Fever of unknown origin Young adult Child Aged Retrospective Studies Aged 80 and over biology business.industry Retrospective cohort study Middle Aged medicine.disease Neutrophilia Ferritin Early Diagnosis chemistry biology.protein Female medicine.symptom business 030217 neurology & neurosurgery medicine.drug |
| Zdroj: | The Quarterly Journal of Nuclear Medicine and Molecular Imaging. 62 |
| ISSN: | 1827-1936 1824-4785 |
| Popis: | BACKGROUND Fever of unknown origin (FUO) is defined as an illness having fever which lasts at least 3 weeks of duration and is higher than 38.3 oC on several measurements. The causes are infections, malignancies, noninfectious inflammatory diseases and miscellaneous. If [18F]FDG-PET/CT helps the final diagnosis, it is called contributory. The aim of the study is to evaluate the predictor variables effecting a contributory PET/CT for the diagnosis. METHODS This is a retrospective cohort study conducted between June 2006 and May 2015 including 76 patients. The evaluated predictor variables are age, sex, ESR, CRP, fibrinogen, ferritin, albumin, haemoglobin level, platelet count, total leukocyte count, neutrophil percentage, lymphocyte percentage, ALP, LDH, ALAT, ASAT, GGT, total bilirubin, CK, RF, ANA, urinanalysis, chest radiography, abdominal US, lymphadenopathy, duration of fever, comorbid diseases and previous therapies. RESULTS ESR (P=0.001), CRP (P=0.001), fibrinogen (P=0.009), lymphopenia (P |
| Databáze: | OpenAIRE |
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