Advances in management of sickle cell disease
| Autor: | M.B. Agarwal |
|---|---|
| Rok vydání: | 2003 |
| Předmět: |
medicine.medical_specialty
Blood transfusion Adolescent medicine.medical_treatment Genetic enhancement Population Respiratory Tract Diseases Disease Anemia Sickle Cell Antisickling Agents medicine Humans Hydroxyurea Blood Transfusion Intensive care medicine education Child Stroke Erythropoietin education.field_of_study business.industry Infant Newborn Infant Bacterial Infections Syndrome medicine.disease Acute chest syndrome Sickle cell anemia Recombinant Proteins Transplantation Child Preschool Pediatrics Perinatology and Child Health Immunology Acute Disease business Stem Cell Transplantation |
| Zdroj: | Indian journal of pediatrics. 70(8) |
| ISSN: | 0019-5456 |
| Popis: | Sickle cell disease is numerically as common as thalassaemia. However, it affects relatively under privileged population i.e. tribal population belonging to economically poor class and having inadequate access to education and modem health facilities. A recent explosion acknowledged in understanding the pathogenesis of this disease has lead to newer dimensions in treatment. Some of these viz. prevention of overwhelming bacterial infection, present indications and controversies regarding blood transfusion, prevention of stroke, acute chest syndrome, hydroxyurea therapy — probably the best disease modifying agent at the moment, stem cell transplantation — a cure and certain promising experimental therapies including gene therapy have been discussed in this review. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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