DObesity: Relationship between vitamin D deficiency, obesity and sclerostin as a novel biomarker of bone metabolism
| Autor: | Doreen N. Younan, Eman Z. Azzam, Mohamed Nabil Ata, Tarek Salem, Ahmed Alaa Abdul-Aziz |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2019 |
| Předmět: |
medicine.medical_specialty
Sclerostin Bone metabolism Endocrinology Diabetes and Metabolism 030209 endocrinology & metabolism Overweight lcsh:Diseases of the endocrine glands. Clinical endocrinology vitamin D deficiency Bone remodeling 03 medical and health sciences chemistry.chemical_compound 0302 clinical medicine Endocrinology Insulin resistance Internal medicine medicine Vitamin D and neurology 030212 general & internal medicine Obesity Vitamin D lcsh:RC648-665 business.industry medicine.disease chemistry Biomarker (medicine) medicine.symptom business Research Paper |
| Zdroj: | Journal of Clinical & Translational Endocrinology Journal of Clinical & Translational Endocrinology, Vol 17, Iss, Pp-(2019) |
| ISSN: | 2214-6237 |
| Popis: | Aim: To study the relationship between obesity, insulin resistance, vitamin D deficiency and sclerostin as a bone biomarker. Materials and methods: Cross-section study of 75 subjects grouped into 3 groups; obese (n = 31), overweight (n = 23) and normal (n = 21) subjects. Sclerostin, fasting insulin, fasting plasma glucose and 25(OH)D were measured and anthropometric measures were taken. Results: 25(OH)D was lower in obese subjects than overweight and control groups (mean ± SD 5.27 ± 5.14 vs. 12.55 ± 6.99 vs.17.65 ± 4.07 ng/L, p |
| Databáze: | OpenAIRE |
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